High Frequency of Non-B Subtypes in Newly Diagnosed HIV-1 Infections in Switzerland
HIV-1 subtypes were determined in newly diagnosed residents of Switzerland. Blood was anonymously collected from patients with a first confirmed positive HIV-1 test result. Viral DNA from the env V3-V5 region was amplified by nested polymerase chain reaction (PCR) and screened for subtype B by heteroduplex mobility assay.
Böni, J +13 more
openaire +4 more sources
HIV-1 non-B subtypes in Italy: a growing trend.
Sequence analysis plays an important role in the management of patients chronically infected with HIV-1. Knowledge of the viral genotype and drug resistance mutations is crucial for the correct management of these patients. From this point of view, the experience of researchers in the HIV-1 field and the introduction of the HIV-1 genotyping resistance ...
Ciccozzi, M +5 more
core +4 more sources
Metabolically Unhealthy Obesity: Novel Subtypes Defined by Integrated Metabolomics and Hematology [PDF]
Objectives: The aim was to identify metabolic subtypes within metabolically unhealthy obesity (MUO) using integrated metabolomics and hematology data and evaluate their differential risks for cardiovascular–kidney–metabolic (CKM)-related outcomes ...
Xuan Huang +5 more
doaj +2 more sources
We evaluated non-B subtypes prevalence,temporal trends and associated epidemiological factors and response to ...
M. Violin +12 more
openaire +2 more sources
Are non-B subtypes less susceptible to antiretroviral drugs? A bioinformatical approach to prediction of non-B subtype susceptibility [PDF]
Address: 1University of Copenhagen, Copenhagen, Denmark, 2Department of Infection & Population Health, Royal Free Campus, University College London, London, UK, 3Department of Infection & Population Health, Royal Free Campus, University College London/University of Copenhagen, London, UK and 4University of Copenhagen/4 Centre for Viral Diseases/KMA ...
Kjær, J +4 more
openaire +1 more source
Increasing Frequency and Transmission of HIV-1 Non-B Subtypes among Men Who Have Sex with Men in the Swiss HIV Cohort Study [PDF]
BACKGROUND In Switzerland, HIV-1 transmission among men who have sex with men (MSM) has been dominated by subtype B, whilst non-B subtypes are commonly attributed to infections acquired abroad among heterosexuals.
Yerly, Sabine +109 more
core +2 more sources
Characteristics of HIV‐1 non‐B subtype infections in Northwest Poland [PDF]
AbstractThe number of non‐B subtype HIV‐1 infections in Europe has been increasing even though major regional differences have been observed. This trend was investigated in northwestern Poland using sequence and epidemiological data from a cohort of 102 HIV‐1‐infected patients from Szczecin, Poland.
Parczewski, Milosz +5 more
openaire +2 more sources
Parkinson Disease Subtype Stability and Eventual Convergence. [PDF]
ABSTRACT Objective Previous research identified distinct Parkinson disease (PD) clinical subtypes of “Motor Only,” “Psychiatric & Motor,” and “Cognitive & Motor” based on comprehensive, multidomain classification. Whether these subtypes reflect distinct trajectories or progressive disease stages remains unknown.
Rosok LM +10 more
europepmc +2 more sources
Raltegravir clinical efficacy against B subtype and non-B subtype HIV-1 is similar [PDF]
Methods Each study was double-blind and randomized; all pts received a background ART regimen (see table in Figure 1). Primary results have been presented for each study. Protocol (P) 004 in treatment-naive pts was a dose-ranging study of RAL vs. efavirenz (EFV) until week 48 after which all pts in RAL groups received 400 mg BID. BENCHMRK-1 and -2 were
Teppler, H +6 more
openaire +1 more source
Human immunodeficiency virus-1 B and non-B subtypes with the same drug resistance pattern respond similarly to antiretroviral therapy [PDF]
We analysed the 12-week virological response to protease inhibitor (PI) or non-nucleoside reverse transcriptase inhibitor (NNRTI) therapy in 1108 patients carrying B or non-B human immunodeficiency virus (HIV)-1 subtypes with matched resistance mutation ...
Casazza, G. +35 more
core +2 more sources

