Results 1 to 10 of about 24,186,788 (290)

Description of the L76V resistance protease mutation in HIV-1 B and "non-B" subtypes. [PDF]

PLoS ONE, 2013
OBJECTIVE: To describe the prevalence of the L76V protease inhibitors resistance-associated mutation (PI-RAM) in relation with patients' characteristics and protease genotypic background in HIV-1 B- and "non-B"-infected patients.
Charlotte Charpentier, Sidonie Lambert-Niclot, Claudia Alteri, Alexandre Storto, Philippe Flandre, Valentina Svicher, Carlo-Federico Perno, Françoise Brun-Vézinet, Vincent Calvez, Anne-Geneviève Marcelin, Francesca Ceccherini-Silberstein, Diane Descamps   +11 more
doaj   +7 more sources

Epidemiological and phylogenetic analysis for non-B subtypes of human immunodeficiency virus type 1 in Busan, Korea [PDF]

Scientific Reports, 2021
Recent data on non-B subtypes’ epidemiology among patients infected with human immunodeficiency virus-1 (HIV-1) in Korea are lacking. We aimed to assess the changing trends in the epidemiology of non-B subtypes of HIV-1 in Korea using ...
Jeong Eun Lee, Soon Ok Lee, Shinwon Lee, Sohee Park, Hyung-Hoi Kim, Kyung-Hwa Shin, Jin Suk Kang, Sun Hee Lee   +7 more
doaj   +2 more sources

Subtype-specific and co-occurring genetic alterations in B-cell non-Hodgkin lymphoma

Haematologica, 2021
B-cell non-Hodgkin lymphoma (B-NHL) encompasses multiple clinically and phenotypically distinct subtypes of malignancy with unique molecular etiologies.
Man Chun John Ma, Saber Tadros, Alyssa Bouska, Tayla Heavican, Haopeng Yang, Qing Deng, Dalia Moore, Ariz Akhter, Keenan Hartert, Neeraj Jain, Jordan Showell, Sreejoyee Ghosh, Lesley Street, Marta Davidson, Christopher Carey, Joshua Tobin, Deepak Perumal, Julie M. Vose, Matthew A. Lunning, Aliyah R. Sohani, Benjamin J. Chen, Shannon Buckley, Loretta J. Nastoupil, R. Eric Davis, Jason R. Westin, Nathan H. Fowler, Samir Parekh, Maher Gandhi, Sattva Neelapu, Douglas Stewart, Kapil Bhalla, Javeed Iqbal, Timothy Greiner, Scott J. Rodig, Adnan Mansoor, Michael R. Green   +35 more
doaj   +1 more source

High Diversity and Transmission Dynamics of HIV-1 Non-C Subtypes in Bangladesh

Tropical Medicine and Infectious Disease, 2023
Genetic diversity and molecular epidemiology of HIV are directly relevant to HIV transmission. We report here the genetic diversity and transmission dynamics of non-C subtypes of HIV-1 strains detected in Bangladeshi key populations. Sequence analysis of
Md. Safiullah Sarker, Rubiyat Jahan
doaj   +1 more source

Functional diversification and dynamics of CAR-T cells in patients with B-ALL

Cell Reports, 2023
Summary: Understanding of cellular evolution and molecular programs of chimeric antigen receptor-engineered (CAR)-T cells post-infusion is pivotal for developing better treatment strategies.
Zongcheng Li, Lei Zhao, Yuanyuan Zhang, Li Zhu, Wei Mu, Tong Ge, Jin Jin, Jiaqi Tan, Jiali Cheng, Jue Wang, Na Wang, Xiaoxi Zhou, Liting Chen, Zhilin Chang, Chen Liu, Zhilei Bian, Bing Liu, Lilin Ye, Yu Lan, Liang Huang, Jianfeng Zhou   +20 more
doaj   +1 more source

A combination of the activation marker CD86 and the immune checkpoint marker B and T lymphocyte attenuator (BTLA) indicates a putative permissive activation state of B cell subtypes in healthy blood donors independent of age and sex

BMC Immunology, 2020
Background The use of anti-B cell based therapies in immune-mediated diseases targeting general B cell markers or molecules important for B cell function has increased the clinical needs of monitoring B cell subpopulations.
Susanne Axelsson, Anders Magnuson, Anna Lange, Aseel Alshamari, Elisabeth Hultgren Hörnquist, Olof Hultgren   +5 more
doaj   +1 more source

Specific expression of novel long non-coding RNAs in high-hyperdiploid childhood acute lymphoblastic leukemia. [PDF]

PLoS ONE, 2017
Pre-B cell childhood acute lymphoblastic leukemia (pre-B cALL) is a heterogeneous disease involving many subtypes typically stratified using a combination of cytogenetic and molecular-based assays.
Mathieu Lajoie, Simon Drouin, Maxime Caron, Pascal St-Onge, Manon Ouimet, Romain Gioia, Marie-Hélène Lafond, Ramon Vidal, Chantal Richer, Karim Oualkacha, Arnaud Droit, Daniel Sinnett   +11 more
doaj   +1 more source

Specialized DNA Structures Act as Genomic Beacons for Integration by Evolutionarily Diverse Retroviruses

Viruses, 2023
Retroviral integration site targeting is not random and plays a critical role in expression and long-term survival of the integrated provirus. To better understand the genomic environment surrounding retroviral integration sites, we performed a meta ...
Hinissan P. Kohio, Hannah O. Ajoge, Macon D. Coleman, Emmanuel Ndashimye, Richard M. Gibson, Eric J. Arts, Stephen D. Barr   +6 more
doaj   +1 more source

Computed Tomography Imaging-Based Radiogenomics Analysis Reveals Hypoxia Patterns and Immunological Characteristics in Ovarian Cancer

Frontiers in Immunology, 2022
PurposeThe hypoxic microenvironment is involved in the tumorigenesis of ovarian cancer (OC). Therefore, we aim to develop a non-invasive radiogenomics approach to identify a hypoxia pattern with potential application in patient prognostication ...
Songwei Feng, Tianyi Xia, Yu Ge, Ke Zhang, Xuan Ji, Shanhui Luo, Yang Shen   +6 more
doaj   +1 more source

HIV subtype, epidemiological and mutational correlations in patients from Paraná, Brazil

Brazilian Journal of Infectious Diseases, 2010
Objective: Analyze patients with HIV infection from Curitiba, Paraná, their epidemiological characteristics and HIV RAM. Methods: Patients regularly followed in an ID Clinic had their medical data evaluated and cases of virological failure were analyzed ...
Monica Maria Gomes da Silva, MD, MSc, Flavio Queiroz Telles, MD, MSc, PhD, Clovis Arns da Cunha, MD, MSc, Frank S. Rhame, MD   +3 more
doaj   +1 more source