Results 11 to 20 of about 24,186,788 (290)

Temporal trends in the Swedish HIV-1 epidemic: increase in non-B subtypes and recombinant forms over three decades. [PDF]

PLoS ONE, 2014
BACKGROUND: HIV-1 subtype B (HIV-1B) still dominates in resource-rich countries but increased migration contributes to changes in the global subtype distribution. Also, spread of non-B subtypes within such countries occurs.
Ujjwal Neogi, Amanda Häggblom, Michele Santacatterina, Göran Bratt, Magnus Gisslén, Jan Albert, Anders Sonnerborg   +6 more
doaj   +3 more sources

Improved Virological Outcome in White Patients Infected With HIV-1 Non-B Subtypes Compared to Subtype B [PDF]

Clinical Infectious Diseases, 2011
Antiretroviral compounds have been predominantly studied in human immunodeficiency virus type 1 (HIV-1) subtype B, but only ~10% of infections worldwide are caused by this subtype. The analysis of the impact of different HIV subtypes on treatment outcome is important.
Scherrer Alexandra U, Ledergerber Bruno, von Wyl Viktor, Böni Jürg, Yerly Sabine, Klimkait Thomas, Bürgisser Philippe, Rauch Andri, Hirschel Bernard, Cavassini Matthias, Elzi Luigia, Vernazza Pietro L, Bernasconi Enos, Held Leonhard, Günthard Huldrych F, the Swiss HIV Cohort Study, Bernasconi E, Ledergerber B, Bonhoeffer S, Günthard HF   +19 more
openaire   +11 more sources

HIV-1 subtype diversity and phylogenetic insight into non-B subtype transmission in Slovenia, 1989-2013 [PDF]

Acta Dermatovenerologica Alpina Pannonica et Adriatica, 2023
Disease progression, drug resistance mutations, and treatment strategies may vary by HIV-1 subtype. This study determined HIV-1 subtypes circulating in Slovenia, a Central European country with an HIV-1 epidemic driven by men who have sex with men, focusing on molecular epidemiology of non-B subtypes.A total of 367 HIV-1 sequences were included ...
Mlakar, Jana, Lunar, Maja M., Abecasis, Ana B., Vandamme, Anne-Mieke, Tomazic, Janez, Vovko, Tomaz D., Pecavar, Blaz, Turel, Gabriele, Poljak, Mario   +8 more
openaire   +4 more sources

The Role of Migration and Domestic Transmission in the Spread of HIV-1 Non-B Subtypes in Switzerland [PDF]

The Journal of Infectious Diseases, 2011
Background. By analyzing human immunodeficiency virus type 1 (HIV-1) pol sequences from the Swiss HIV Cohort Study (SHCS), we explored whether the prevalence of non-B subtypes reflects domestic transmission or migration patterns. Methods. Swiss non-B sequences and sequences collected abroad were pooled to construct maximum likelihood trees, which were ...
von Wyl, Viktor, Kouyos, Roger D., Yerly, Sabine, Böni, Jürg, Shah, Cyril, Bürgisser, Philippe, Klimkait, Thomas, Weber, Rainer, Hirschel, Bernard, Cavassini, Matthias, Staehelin, Cornelia, Battegay, Manuel, Vernazza, Pietro L., Bernasconi, Enos, Ledergerber, Bruno, Bonhoeffer, Sebastian, Günthard, Huldrych F., Swiss HIV Cohort Study   +17 more
openaire   +10 more sources

Phenotypic and Genotypic Co-receptor Tropism Testing in HIV-1 Epidemic Region of Tanzania Where Multiple Non-B Subtypes Co-circulate [PDF]

Frontiers in Microbiology, 2021
HIV human immunodeficiency virus type I (HIV-1) entry inhibitor potency is dependent on viral co-receptor tropisms and thereby tropism determination is clinically important.
George P. Judicate, Godfrey Barabona, Doreen Kamori, Macdonald Mahiti, Toong Seng Tan, Seiya Ozono, Amina Shaban Mgunya, Takeo Kuwata, Shuzo Matsushita, Bruno Sunguya, Bruno Sunguya, Eligius Lyamuya, Eligius Lyamuya, Kenzo Tokunaga, Kenzo Tokunaga, Takamasa Ueno, Takamasa Ueno   +16 more
doaj   +2 more sources

Do HIV‐1 non‐B subtypes differentially impact resistance mutations and clinical disease progression in treated populations? Evidence from a systematic review

Journal of the International AIDS Society, 2014
There are 31 million adults living with HIV‐1 non‐B subtypes globally, and about 10 million are on antiretroviral therapy (ART). Global evidence to guide clinical practice on ART response in HIV‐1 non‐B subtypes remains limited.
Madhavi Bhargava, Jorge Martinez Cajas, Mark A Wainberg, Marina B Klein, Nitika Pant Pai   +4 more
doaj   +2 more sources

High prevalence of non‐B HIV‐1 subtypes in seamen and their sexual partners in Croatia

Journal of Medical Virology, 2009
AbstractTravel influences the spread of non‐B subtypes of HIV in Europe. The aim of this study was to assess whether the spread of non‐B subtypes occurred in Croatia, a country with a low level HIV infection. Phylogenetic analysis of the reverse transcriptase and protease genes was undertaken in 145 Croatian patients with the following risks for HIV ...
Ramirez-Piedad, Martha Kathleen, Lepej, Snjezana Zidovec, Yerly Ferrillo, Sabine, Begovac, Josip   +3 more
core   +5 more sources

Tools to Quantify and Characterize the Persistent Reservoir in People with HIV-1: Focus on Non-B Subtypes [PDF]

Viruses
Human immunodeficiency virus type 1 (HIV-1) continues to be a major global health burden. Combination antiretroviral therapy (cART) effectively abrogates HIV-1 replication and has transformed HIV-1 infection from a fatal to chronic disease. While ART can
Zora Sinay, Annefien Tiggeler, Robert-Jan Palstra, Tokameh Mahmoudi   +3 more
doaj   +2 more sources

Characteristics and spread to the native population of HIV-1 non-B subtypes in two European countries with high migration rate [PDF]

BMC Infect Dis, 2015
Background: Non-B subtypes account for at least 50 % of HIV-1 infections diagnosed in Belgium and Luxembourg. They are considered to be acquired through heterosexual contacts and infect primarily individuals of foreign origin.
Jean-Yves Servais, Chris Verhofstede, Seguin-Devaux, Carole, Bercoff, Danielle Perez, Katrien Fransen, Dauwe, Kenny, Servais, Jean-Yves, Schauvliege, Marlies, Marlies Schauvliege, Mortier, Virginie, Annelies Van Den Heuvel, Carole Seguin-Devaux, Fransen, Katrien, Kenny Dauwe, Virginie Mortier, Danielle Perez Bercoff, Kenny Dauwe, Verhofstede, Chris, Perez Bercoff, Danielle, Van den Heuvel, Annelies   +19 more
core   +3 more sources

Detection of HIV Type 1 Non-B Subtypes in Sicily, Italy

AIDS Research and Human Retroviruses, 2004
To evaluate the presence of HIV-1 non-B subtypes in Sicily, we sequenced and genotyped HIV-1 PR and RT regions of the pol gene using plasma from 169 HIV-1-infected adult patients. All samples were obtained from a study of antiretroviral-associated resistance mutations resulting in virological failure during highly active antiretroviral therapy (HAART).
Fabio, Tramuto, Francesco, Vitale, Filippa, Bonura, Nino, Romano   +3 more
openaire   +3 more sources