Results 251 to 260 of about 262,938 (280)
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Incorporation of Non‐canonical Amino Acids into 2,5‐Diketopiperazines by Cyclodipeptide Synthases

Angewandte Chemie International Edition, 2018
AbstractThe manipulation of natural product biosynthetic pathways is a powerful means of expanding the chemical diversity of bioactive molecules. 2,5‐diketopiperazines (2,5‐DKPs) have been widely developed by medicinal chemists, but their biological production is yet to be exploited.
Nicolas Canu   +7 more
openaire   +3 more sources

Biosynthesis and biotechnological application of non-canonical amino acids: Complex and unclear

Biotechnology Advances, 2018
Compared with the better-studied canonical amino acids, the distribution, metabolism and functions of natural non-canonical amino acids remain relatively obscure. Natural non-canonical amino acids have been mainly discovered in plants as secondary metabolites that perform diversified physiological functions.
Huibin Zou   +6 more
openaire   +2 more sources

Tumour fatty acid metabolism in the context of therapy resistance and obesity

Nature Reviews Cancer, 2021
Andrew J Hoy   +2 more
exaly  

Mechanisms of retinoic acid signalling and its roles in organ and limb development

Nature Reviews Molecular Cell Biology, 2015
Thomas J Cunningham, Gregg Duester
exaly  

Pharmacological modulation of nucleic acid sensors — therapeutic potential and persisting obstacles

Nature Reviews Drug Discovery, 2019
Claire Vanpouille-Box, Lorenzo Galluzzi
exaly  

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