To Be or Not To Be a Molecular Ion: The Role of the Solvent in Photoionization of Arginine. [PDF]
, 2019 Application of photoionization mass spectroscopy, a technique capable of assessing protonation states in complex molecules in the gas phase, is challenging for arginine due to its fragility. We report photoionization efficiencies in the valence region of
Ahmed, Musahid +7 more
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Red-Shifted Aequorin Variants Incorporating Non-Canonical Amino Acids: Applications in In Vivo Imaging. [PDF]
PLoS ONE, 2016 The increased importance of in vivo diagnostics has posed new demands for imaging technologies. In that regard, there is a need for imaging molecules capable of expanding the applications of current state-of-the-art imaging in vivo diagnostics.
Kristen M Grinstead +7 more
doaj +1 more source
Divergent functional roles of D-amino acids secreted by Vibrio cholerae [PDF]
, 2018 The L-forms of amino acids are used in all kingdoms of life to synthesize proteins. However, the bacterium Vibriocholerae, the causative agent of cholera, produces D-amino acids which are released to the environment at millimolar concentrations.We ...
Felipe Cava
core
The Endoplasmic Reticulum Glucosyltransferase Recognizes Nearly Native Glycoprotein Folding Intermediates [PDF]
, 2004 The UDP-Glc:glycoprotein glucosyltransferase (GT), a key player in the endoplasmic reticulum (ER) quality control of glycoprotein folding, only glucosylates glycoproteins displaying non-native conformations.
Caramelo, Julio Javier +3 more
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NASSAM: a server to search for and annotate tertiary interactions and motifs in three-dimensional structures of complex RNA molecules [PDF]
, 2012 Similarities in the 3D patterns of RNA base interactions or arrangements can provide insights into their functions and roles in stabilization of the RNA 3D structure.
Ban +21 more
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Quantitative profiling of selective Sox/POU pairing on hundreds of sequences in parallel by Coop-seq [PDF]
, 2016 © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research. Cooperative binding of transcription factors is known to be important in the regulation of gene expression programs conferring cellular identities.
Chang, Yiming K +8 more
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Nature Communications, 2020 Chemical modification of proteins can be used to decipher function or use that function for therapeutic purposes. Here, the authors insert synthetic peptides via tandem protein trans-splicing to add post-translational modifications or non-canonical amino
K. K. Khoo +9 more
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Do Amino Acid Antiporters Have Asymmetric Substrate Specificity?
Biomolecules, 2023 Amino acid antiporters mediate the 1:1 exchange of groups of amino acids. Whether substrate specificity can be different for the inward and outward facing conformation has not been investigated systematically, although examples of asymmetric transport ...
Gregory Gauthier-Coles +3 more
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Large-scale identification and characterization of alternative splicing variants of human gene transcripts using 56 419 completely sequenced and manually annotated full-length cDNAs [PDF]
, 2006 We report the first genome-wide identification and characterization of alternative splicing in human gene transcripts based on analysis of the full-length cDNAs.
Jun-ichi Takeda +65 more
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New Insights Into the Mechanisms and Biological Roles of D-Amino Acids in Complex Eco-Systems
Frontiers in Microbiology, 2018 In the environment bacteria share their habitat with a great diversity of organisms, from microbes to humans, animals and plants. In these complex communities, the production of extracellular effectors is a common strategy to control the biodiversity by ...
Alena Aliashkevich +2 more
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