Results 31 to 40 of about 17,217,890 (291)

Update on the treatment of metastatic clear cell and non-clear cell renal cell carcinoma [PDF]

Biomarker Research, 2015
The advent of new knowledge surrounding the molecular pathology of renal-cell carcinoma (RCC) has culminated in a number of emerging targeted therapies. In just the last year, several new studies have been able to translate our understanding of tumor biology into significantly improved outcomes in patients with advanced RCC.
Xu, Kevin Y, Wu, Shenhong
openaire   +2 more sources

Current perspectives on systemic therapy for metastatic non-clear cell renal cell carcinoma [PDF]

CellR4, 2020
The improvements in the knowledge of the underlying biology of renal cell carcinoma (RCC) has led to consider this disease as a group of different entities characterized by their pathological phenotype, and the particular features exhibited in their ...
J. González, G. Ciancio
doaj   +1 more source

UBE2QL1 is Disrupted by a Constitutional Translocation Associated with Renal Tumor Predisposition and is a Novel Candidate Renal Tumor Suppressor Gene [PDF]

, 2013
Investigation of rare familial forms of renal cell carcinoma (RCC) has led to the identification of genes such as VHL and MET that are also implicated in the pathogenesis of sporadic RCC. In order to identify a novel candidate renal tumor suppressor gene,
Hodgson, S, Morris, Mark R., Turnell, Andrew S., Woodward, ER, Prigmore, Elena, Woodward, Emma R.; id_orcid, Wake, NC, Wake, Naomi C., Gribble, Susan M., Ricketts, Christopher J., Skytte, AB, Brown, Michael, Banks, RE, Morris, MR, Prigmore, E, Maher, ER, Woodward, Emma R., Clarke, Noel, Hodgson, Shirley, Skytte, Anne-bine, Ricketts, CJ, Turnell, AS, Brown, Michael; id_orcid, Maher, Eamonn R., Clarke, N, Banks, Rosamonde E., Gribble, SM, Brown, M, Skytte, Anne Bine, Wake, N, Clarke, Noel W, Brown, Michael D, Ricketts, C, Woodward, E, Skytte, A-B, Maher, E, Morris, M, Banks, R, Turnell, A, Gribble, S   +39 more
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Clear cell renal cell carcinoma and papillary renal cell carcinoma: differentiation of distinct histological types with multiphase CT [PDF]

, 2013
PURPOSEConventional clear cell renal cell carcinoma (ccRCC) and papillary renal cell carcinoma (pRCC) have different behavioral characteristics and clinical management strategies (nephrectomy vs. nephron-sparing surgery).
David Laszlo Tarnoki, Peter Nyirady, Bence Fejer, Attila Szendroi, A. Marcell Szasz, Dora Kekesi, Viktor Berczi, Pal Bata, Janos Gyebnar, Adam Domonkos Tarnoki, Kinga Karlinger   +10 more
core   +1 more source

Resistance after chronic application of the HDAC-inhibitor valproic acid is associated with elevated Akt activation in renal cell carcinoma in vivo [PDF]

, 2013
Targeted drugs have significantly improved the therapeutic options for advanced renal cell carcinoma (RCC). However, resistance often develops, negating the benefit of these agents.
Eva Juengel, Jasmina Makarević, Axel Haferkamp, Georg Bartsch, Roman A Blaheta, Jüngel, Eva, Nelson, Karen, Blaheta, Roman A., Igor Tsaur, Makarević, Jasmina, Karen Nelson, Tsaur, Igor, Haferkamp, Axel, Bartsch, Georg, Juengel Eva, Makarević Jasmina, Blaheta Roman A., Nelson Karen, Tsaur Igor, Haferkamp Axel, Bartsch Georg   +20 more
core   +2 more sources

Evaluation of the Relative Enhancement Ratio and Morphologic Findings on Biphasic CT to Differentiate Clear Cell and Non-Clear Cell Renal Cell Carcinoma

Siriraj Medical Journal, 2016
Objective: To differentiate clear cell and non-clear cell renal cell carcinoma (RCC) using enhancement pattern, relative enhancement ratio and associated findings on CT scan.
Nithida Na Songkhla
doaj   +2 more sources

A pyramidal deep learning pipeline for kidney whole-slide histology images classification

Scientific Reports, 2021
Renal cell carcinoma is the most common type of kidney cancer. There are several subtypes of renal cell carcinoma with distinct clinicopathologic features.
Hisham Abdeltawab, Fahmi Khalifa, Mohammed Mohammed, Liang Cheng, Dibson Gondim, Ayman El-Baz   +5 more
doaj   +1 more source

Safety and efficacy of sunitinib for advanced non‐clear cell renal cell carcinoma [PDF]

Asia-Pacific Journal of Clinical Oncology, 2015
This study evaluated the safety and efficacy of sunitinib in the treatment of advanced non-clear cell renal cell carcinoma.Thirty-seven Chinese patients with advanced non-clear cell renal cell carcinoma were enrolled from October 2008 to October 2013. Sunitinib monotherapy was administered in repeated 6-week cycles of daily oral administration of 50 mg
Hong-Zhe, Shi, Jun, Tian, Chang-Ling, Li
openaire   +2 more sources

Significant different imaging characteristics between patients with clear-cell and non-clear-cell renal cell carcinoma.

, 2018
Significant different imaging characteristics between patients with clear-cell and non-clear-cell renal cell carcinoma.
Simone Bier (5117315), Georg Bier (848051), Johann-Martin Hempel (3445778), Ahmed Othman (758425), Ulrike Ernemann (574969), Malte Niklas Bongers (5117318)   +5 more
core   +1 more source

Non-muscle-invasive clear cell carcinoma of the urinary bladder: Is cystectomy necessary? [PDF]

, 2019
We report the clinical presentation, histological findings and management of a 49-year-old female patient with non-muscle-invasive clear cell carcinoma of the urinary bladder. In the literature, there are only seven such case reports.
Sanjeev Madaan, Tamani Jayawardhana, Hossam Alsayed, Amit Goel   +3 more
core   +1 more source