Results 41 to 50 of about 17,217,890 (291)

Clinical, molecular, and genetic correlates of lymphatic spread in clear cell renal cell carcinoma [PDF]

, 2012
While it is well known that clear cell renal cell carcinoma (ccRCC) that presents with lymphatic spread is associated with an extremely poor prognosis, its molecular and genetic biology is poorly ...
Zomorodian, Nazy, Seligson, David B, Rampersaud, Edward N, Klatte, Tobias, Kroeger, Nils, Birkhäuser, Frédéric D, Belldegrun, Arie S, Leppert, John T, Kabbinavar, Fairooz F, Pantuck, Allan J, Rao, P Nagesh   +10 more
core   +1 more source

Evaluating hemorrhage in renal cell carcinoma using susceptibility weighted imaging. [PDF]

PLoS ONE, 2013
BACKGROUND: Intratumoral hemorrhage is a frequent occurrence in renal cell carcinoma and is an indicator of tumor subtype. We hypothesize that susceptibility weighted imaging (SWI) is sensitive to hemorrhage in renal cell carcinoma and can give a more ...
Wei Xing, Xiaozhou He, Mohammad A Kassir, Jie Chen, Jiule Ding, Jun Sun, Jiani Hu, Zishu Zhang, E Mark Haacke, Yongming Dai   +9 more
doaj   +1 more source

Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma [PDF]

, 2010
Background: The enhancer of zeste homolog 2 (EZH2) gene exerts oncogene-like activities and its (over)expression has been linked to several human malignancies. Here, we studied a possible association between EZH2 expression and prognosis in patients with
Johannes Hüsing, Wagener, Nina, Hüsing Johannes, Karin Hoppe-Seyler, Hoppe-Seyler Felix, Peter Schirmacher, Hoppe-Seyler, Karin, Pfitzenmaier, Jesco, Macher-Göppinger, Stephan, Jesco Pfitzenmaier, Hohenfellner, Markus, Hüsing, Johannes, Haferkamp, Axel, Haferkamp Axel, Stephan Macher-Goeppinger, Maria Pritsch, Wagener Nina, Pritsch Maria, Axel Haferkamp, Schirmacher Peter, Nina Wagener, Hoppe-Seyler Karin, Hohenfellner Markus, Felix Hoppe-Seyler, Hoppe-Seyler, Felix, Pfitzenmaier Jesco, Macher-Goeppinger Stephan, Markus Hohenfellner, Pritsch, Maria, Schirmacher, Peter   +29 more
core   +2 more sources

Redefining Renal Cell Carcinoma: A Molecular Perspective on Classification and Clinical Implications [PDF]

, 2023
Renal cell carcinoma (RCC) is the most common primary tumour of the kidney. RCC is a clinically and pathologically heterogenous entity, which has traditionally been classified under two broad categories: clear-cell and non-clear cell.
Robert Wightman, Jeffrey Graham, Piotr Czaykowski, Ian W Gibson, Arjun Athreya Raghavan   +4 more
core   +1 more source

Differentiation of clear cell and non clear cell renal cell carcinoma through high-frame-rate contrast-enhanced ultrasound

Scientific Reports
Objective To evaluate the value of high-frame-rate contrast-enhanced ultrasound (H-CEUS) in differentiating between clear cell renal cell carcinoma (ccRCC) and non-clear cell renal cell carcinoma (nccRCC).
Wenxin Yuan, Jingling Wang, Hailan Wu, Long Gao, Zhixing Liu, Weiping Zhang   +5 more
doaj   +1 more source

Cell surface engineering of renal cell carcinoma with glycosylphosphatidylinositol-anchored TIMP-1 blocks TGF-beta 1 activation and reduces regulatory ID gene expression [PDF]

, 2012
Tissue inhibitor of metalloproteinase 1 (TIMP-1) controls matrix metalloproteinase activity through 1:1 stoichiometric binding. Human TIMP-1 fused to a glycosylphosphatidylinositol (GPI) anchor (TIMP-1-GPI) shifts the activity of TIMP-1 from the ...
Notohamiprodjo, Susan, Jaeckel, Carsten, Djafarzadeh, Roghieh, Hofstetter, Monika, Nelson, Peter J., Rieth, Nicole   +5 more
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Temsirolimus for patients with metastatic renal cell carcinoma : outcomes in patients receiving temsirolimus within a compassionate use program in a tertiary referral center [PDF]

, 2014
Aim: Temsirolimus has shown efficacy as first-line treatment of patients with metastatic renal cell carcinoma and poor prognostic features. The efficacy of temsirolimus in other clinical settings, such as second-line therapy, is unclear.
Pascoe, Jennifer, Afshar, Mehran, Porfiri, Emilio, Whitmarsh, Sue, James, Nicholas D.   +4 more
core   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Molecular Drivers of Chromophobe Renal Cell Carcinoma Revealed Through Genomic Analysis Using AACR Project GENIE

Life
Chromophobe renal cell carcinoma (chRCC) is a distinct subtype of non–clear cell renal cell carcinoma (ncRCC), arising from intercalated cells of the distal nephron collecting ducts.
Abbi Gobel, Grace S. Saglimbeni, Eugene Manu, Nikhita Tandon, Tyson J Morris, Akaash Surendra, Beau Hsia, Peter T. Silberstein, Khalid Bashir, Abubakar Tauseef   +9 more
doaj   +1 more source