Results 161 to 170 of about 970,725 (346)

Non-coding RNA networks in cancer

Nature Reviews. Cancer, 2017
E. Anastasiadou, Leni S. Jacob, F. Slack
semanticscholar   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Glutathiones’ life in multi-cancers: especially their potential micropetides in liver hepatocellular carcinoma

Discover Oncology
Background Glutathione plays critical roles in detoxifying xenobiotics, cell signaling, cell death and the antioxidant defence in an emerging body of evidence, the most abundant intracellular low molecular weight thiol in tissues.
Didi Ma, Zhenguo Wu, Mengying Zhang, Jian Mao, Wenqin Xu, Lan Jiang, Zuzhen Wang   +6 more
doaj   +1 more source

Potential structural role of non-coding and coding RNAs in the organization of the cytoskeleton at the vegetal cortex of Xenopusoocytes [PDF]

, 2005

openalex   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Long Non-coding RNA

, 2015
Rapid development in genome-wide transcriptional analyses has led to the discovery of a large number of non-coding transcripts, also called long non-coding RNA (lncRNA). LncRNAs harbor biological activities including regulation of protein-coding gene expression at epigenetic, transcriptional and post-transcriptional levels.
openaire   +2 more sources

Intratumoral microbiota: implications for cancer progression and treatment

Frontiers in Microbiology
The human body has a diverse range of microbiota that influences human physiological processes and alters disease risk, involving cancer. Metagenomic sequencing investigations have revealed that the microbiota is an element of the tumor microenvironment,
Zehang Xie, Zehang Xie, Zhenguo Wu, Zhenguo Wu, Yan Liu, Yan Liu, Yu Gu, Yu Gu, Jiahao Niu, Jiahao Niu, Kun Lv, Kun Lv   +11 more
doaj   +1 more source

EFFICIENT ANNOTATION OF NON-CODING RNA STRUCTURES INCLUDING PSEUDOKNOTS VIA AUTOMATED FILTERS [PDF]

, 2006
Chunmei Liu, Yinglei Song, Ping Hu, Russell L. Malmberg, Liming Cai   +4 more
openalex   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

About Non – Coding Rnas

, 2018
Abstract— The central dogma of molecular biology states that DNA makes RNA and RNA makes protein. Recently, a large number of RNAs have been identified in animal and plants that have little or no protein – coding potential. Such RNA molecules have been discovered by the extensive applications of high – throughput sequencing technology.
openaire   +2 more sources