Results 11 to 20 of about 11,605,954 (262)

Blood Transcriptome Analysis of Septic Patients Reveals a Long Non-Coding Alu-RNA in the Complement C5a Receptor 1 Gene [PDF]

open access: yes, 2022
Many severe inflammation conditions are complement-dependent with the complement component C5a-C5aR1 axis as an important driver. At the RNA level, the blood transcriptome undergoes programmed expression of coding and long non-coding RNAs to combat ...
Steinar Daae Johansen   +15 more
core   +1 more source

Activity-Dependent Non-Coding RNA MAPK Interactome of the Human Epileptic Brain

open access: yes, 2023
The human brain has evolved to have extraordinary capabilities, enabling complex behaviors. The uniqueness of the human brain is increasingly posited to be due in part to the functions of primate-specific, including human-specific, long non-coding RNA ...
Fabien Dachet   +3 more
core   +1 more source

The antiviral activity of a small molecule drug targeting the NSP1-ribosome complex against Omicron, especially in elderly patients

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
IntroductionWith the emergence of SARS-CoV-2 mutant strains, especially the epidemic of Omicron, it continues to evolve to strengthen immune evasion. Omicron BQ.
Min Shen   +5 more
doaj   +1 more source

An improved method for surface immobilisation of RNA: application to small Non-Coding RNA - mRNA pairing [PDF]

open access: yes, 2013
Characterisation of RNA and its intermolecular interactions is increasing in importance as the inventory of known RNA functions continues to expand. RNA-RNA interactions are central to post-transcriptional gene regulation mechanisms in bacteria, and the ...
Darren M. Gowers (485354)   +29 more
core   +2 more sources

Acknowledgement to Reviewers of Non-Coding RNA in 2017

open access: yesNon-Coding RNA, 2018
Peer review is an essential part in the publication process, ensuring that Non-Coding RNA maintains high quality standards for its published papers.[...]
Non-Coding RNA Editorial Office
doaj   +1 more source

The miR-28-5p Targetome Discovery Identified SREBF2 as One of the Mediators of the miR-28-5p Tumor Suppressor Activity in Prostate Cancer Cells

open access: yesCells, 2020
miR-28-5p is downregulated in some tumor tissues in which it has been demonstrated to have tumor suppressor (TS) activity. Here, we demonstrate that miR-28-5p acts as a TS in prostate cancer (PCa) cells affecting cell proliferation/survival, as well as ...
Sofia Fazio   +7 more
doaj   +1 more source

Identification and characterization of novel conserved RNA structures in Drosophila

open access: yesBMC Genomics, 2018
Background Comparative genomics approaches have facilitated the discovery of many novel non-coding and structured RNAs (ncRNAs). The increasing availability of related genomes now makes it possible to systematically search for compensatory base changes –
Rebecca Kirsch   +5 more
doaj   +1 more source

Combined VEGFR and MAPK pathway inhibition in angiosarcoma

open access: yesScientific Reports, 2021
Angiosarcoma is an aggressive malignancy of endothelial cells that carries a high mortality rate. Cytotoxic chemotherapy can elicit clinical responses, but the duration of response is limited.
Michael J. Wagner   +12 more
doaj   +1 more source

Long Non-Coding RNA-Ribonucleoprotein Networks in the Post-Transcriptional Control of Gene Expression

open access: yes, 2020
Although mammals possess roughly the same number of protein-coding genes as worms, it is evident that the non-coding transcriptome content has become far broader and more sophisticated during evolution.
Paola Briata, Roberto Gherzi
core   +1 more source

Long Non-Coding RNA Function in CD4+ T Cells:What We Know and What Next? [PDF]

open access: yes, 2019
The non-coding genome has previously been regarded as "junk" DNA; however, emerging evidence suggests that the non-coding genome accounts for some of the greater biological complexity observed in mammals.
Lagos, Dimitris   +5 more
core   +1 more source

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