Results 21 to 30 of about 688,893 (310)

The antiviral activity of a small molecule drug targeting the NSP1-ribosome complex against Omicron, especially in elderly patients

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
IntroductionWith the emergence of SARS-CoV-2 mutant strains, especially the epidemic of Omicron, it continues to evolve to strengthen immune evasion. Omicron BQ.
Min Shen   +5 more
doaj   +1 more source

An improved method for surface immobilisation of RNA: application to small Non-Coding RNA - mRNA pairing [PDF]

open access: yes, 2013
Characterisation of RNA and its intermolecular interactions is increasing in importance as the inventory of known RNA functions continues to expand. RNA-RNA interactions are central to post-transcriptional gene regulation mechanisms in bacteria, and the ...
Darren M. Gowers (485354)   +29 more
core   +1 more source

Non-Coding RNAs and Cancer [PDF]

open access: yesInternational Journal of Molecular Sciences, 2013
The discovery of the biological relevance of non-coding RNA (ncRNAs) molecules represents one of the most significant advances in contemporary molecular biology. Expression profiling of human tumors, based on the expression of miRNAs and other short or long ncRNAs, has identified signatures associated with diagnosis, staging, progression, prognosis ...
Calore, Federica   +2 more
openaire   +2 more sources

Role of non-coding RNAs and exosomal non-coding RNAs in retinoblastoma progression

open access: yesFrontiers in Cell and Developmental Biology, 2022
Retinoblastoma (RB) is a rare aggressive intraocular malignancy of childhood that has the potential to affect vision, and can even be fatal in some children. While the tumor can be controlled efficiently at early stages, metastatic tumors lead to high mortality.
Nasrin Ahangar Davoodi   +13 more
openaire   +3 more sources

The miR-28-5p Targetome Discovery Identified SREBF2 as One of the Mediators of the miR-28-5p Tumor Suppressor Activity in Prostate Cancer Cells

open access: yesCells, 2020
miR-28-5p is downregulated in some tumor tissues in which it has been demonstrated to have tumor suppressor (TS) activity. Here, we demonstrate that miR-28-5p acts as a TS in prostate cancer (PCa) cells affecting cell proliferation/survival, as well as ...
Sofia Fazio   +7 more
doaj   +1 more source

Non-coding RNAs and retroviruses [PDF]

open access: yesRetrovirology, 2018
Retroviruses can cause severe diseases such as cancer and acquired immunodeficiency syndrome. A unique feature in the life cycle of retroviruses is that their RNA genome is reverse transcribed into double-stranded DNA, which then integrates into the host genome to exploit the host machinery for their benefits.
Xu Zhang   +4 more
openaire   +3 more sources

Acknowledgement to Reviewers of Non-Coding RNA in 2017

open access: yesNon-Coding RNA, 2018
Peer review is an essential part in the publication process, ensuring that Non-Coding RNA maintains high quality standards for its published papers.[...]
Non-Coding RNA Editorial Office
doaj   +1 more source

Identification and characterization of novel conserved RNA structures in Drosophila

open access: yesBMC Genomics, 2018
Background Comparative genomics approaches have facilitated the discovery of many novel non-coding and structured RNAs (ncRNAs). The increasing availability of related genomes now makes it possible to systematically search for compensatory base changes –
Rebecca Kirsch   +5 more
doaj   +1 more source

Non-Coding RNAs in Retinoblastoma [PDF]

open access: yesFrontiers in Genetics, 2019
Retinoblastoma (Rb) is the most common ocular pediatric malignancy that arises from the retina and is caused by a mutation of the two alleles of the tumor suppressor gene, RB1. Although early detection provides the opportunity of controlling the primary tumor with effective therapies, metastatic activity is fatal.
Meropi Plousiou, Ivan Vannini
openaire   +3 more sources

Long Non-Coding RNA-Ribonucleoprotein Networks in the Post-Transcriptional Control of Gene Expression

open access: yes, 2020
Although mammals possess roughly the same number of protein-coding genes as worms, it is evident that the non-coding transcriptome content has become far broader and more sophisticated during evolution.
Paola Briata, Roberto Gherzi
core   +1 more source

Home - About - Disclaimer - Privacy