Results 31 to 40 of about 12,053,900 (263)
Combined VEGFR and MAPK pathway inhibition in angiosarcoma
Scientific Reports, 2021 Angiosarcoma is an aggressive malignancy of endothelial cells that carries a high mortality rate. Cytotoxic chemotherapy can elicit clinical responses, but the duration of response is limited.
Michael J. Wagner +12 more
doaj +1 more source
MALAT1 Long Non-Coding RNA: Functional Implications
, 2020 The mammalian genome is pervasively transcribed and the functional significance of many long non-coding RNA (lncRNA) transcripts are gradually being elucidated.
Disha Aggarwal +2 more
core +1 more source
Long Non-Coding RNA Signatures in Lymphopoiesis and Lymphoid Malignancies
, 2023 Lymphoid cells play a critical role in the immune system, which includes three subgroups of T, B, and NK cells. Recognition of the complexity of the human genetics transcriptome in lymphopoiesis has revolutionized our understanding of the regulatory ...
Mahdi Zavvar +8 more
core +1 more source
Scientific Reports, 2017 Anatomical subdivisions of the human brain can be associated with different neuronal functions. This functional diversification is reflected by differences in gene expression.
Nikolai Hecker +4 more
doaj +1 more source
Microbiology Spectrum, 2023 The spread of multidrug resistant and hypervirulent Klebsiella pneumoniae has recently increased. Phages have been considered alternatives for treating infections caused by tenacious pathogens.
Huaixin Geng +7 more
doaj +1 more source
miR-144/451 in hematopoiesis and beyond [PDF]
ExRNA, 2019 MicroRNAs (miRNAs), a class of 18–25 nucleotide (nt) non-coding RNAs, usually inhibit the expression of their target genes. They are transcribed from endogenous genes and are processed for maturation by multiple pathways.
Ting Wang, Fan Wu, Duonan Yu
doaj +1 more source
, 2020 Out of respect for the institution’s wishes, in agreement with the Non-Coding RNA Editorial Office, and in agreement with the author, this article has been removed from the public record and marked as retracted.
Bert Verheijen
core +1 more source
CRISPR-Cas9 off-targeting assessment with nucleic acid duplex energy parameters
Genome Biology, 2018 Background Recent experimental efforts of CRISPR-Cas9 systems have shown that off-target binding and cleavage are a concern for the system and that this is highly dependent on the selected guide RNA (gRNA) design. Computational predictions of off-targets
Ferhat Alkan +4 more
doaj +1 more source
Frontiers in Genetics, 2020 Recently, a few animals have been frequently reported to have been diagnosed with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Whether they are SARS-CoV-2 intermediate hosts is worthy of great attention.
Min Shen +11 more
doaj +1 more source
The role of noncoding RNAs in cancer lipid metabolism
Frontiers in Oncology, 2022 Research on noncoding ribonucleic acids (ncRNAs) is mostly and broadly focused on microRNAs (miRNAs), cyclic RNAs (circRNAs), and long ncRNAs (lncRNAs), which have been confirmed to play important roles in tumor cell proliferation, invasion, and ...
Ye Wang +39 more
doaj +1 more source