Results 31 to 40 of about 688,893 (310)
Long Non-Coding RNA Function in CD4+ T Cells:What We Know and What Next? [PDF]
, 2019 The non-coding genome has previously been regarded as "junk" DNA; however, emerging evidence suggests that the non-coding genome accounts for some of the greater biological complexity observed in mammals.
Lagos, Dimitris +5 more
core +1 more source
Long Non-Coding RNA Signatures in Lymphopoiesis and Lymphoid Malignancies
, 2023 Lymphoid cells play a critical role in the immune system, which includes three subgroups of T, B, and NK cells. Recognition of the complexity of the human genetics transcriptome in lymphopoiesis has revolutionized our understanding of the regulatory ...
Mahdi Zavvar +8 more
core +1 more source
Combined VEGFR and MAPK pathway inhibition in angiosarcoma
Scientific Reports, 2021 Angiosarcoma is an aggressive malignancy of endothelial cells that carries a high mortality rate. Cytotoxic chemotherapy can elicit clinical responses, but the duration of response is limited.
Michael J. Wagner +12 more
doaj +1 more source
MALAT1 Long Non-Coding RNA: Functional Implications
, 2020 The mammalian genome is pervasively transcribed and the functional significance of many long non-coding RNA (lncRNA) transcripts are gradually being elucidated.
Disha Aggarwal +2 more
core +1 more source
Crosstalk between Long Non-Coding RNA and Spliceosomal microRNA as a Novel Biomarker for Cancer
, 2023 Non-coding RNAs (ncRNAs) play diverse roles in regulating cellular processes and have been implicated in pathological conditions, including cancer, where interactions between ncRNAs play a role.
Maram Arafat, Ruth Sperling
core +1 more source
The Epigenetics of Non-coding RNA [PDF]
, 2011 Summary Non-coding RNAs (ncRNAs) have been implicated in the epigenetic marking of many genes. Short regulatory ncRNAs, including miRNAs, siRNAs, piRNAs and snoRNAs as well as long ncRNAs such as Xist and Air are discussed in light of recent research of mechanisms regulating chromatin marking and RNA editing.
Collins, L., Schönfeld, B., Chen, X.
openaire +2 more sources
Non-Coding RNAs in Muscle Dystrophies [PDF]
International Journal of Molecular Sciences, 2013 ncRNAs are the most recently identified class of regulatory RNAs with vital functions in gene expression regulation and cell development. Among the variety of roles they play, their involvement in human diseases has opened new avenues of research towards the discovery and development of novel therapeutic approaches.
ERRIQUEZ, DANIELA +2 more
openaire +3 more sources
Scientific Reports, 2017 Anatomical subdivisions of the human brain can be associated with different neuronal functions. This functional diversification is reflected by differences in gene expression.
Nikolai Hecker +4 more
doaj +1 more source
Current Status of Regulatory Non-Coding RNAs Research in the Tritryp [PDF]
, 2022 Trypanosomatids are protozoan parasites that cause devastating vector-borne human diseases. Gene expression regulation of these organisms depends on post-transcriptional control in responding to diverse environments while going through multiple ...
Trinidad Barnech, Juan M. +15 more
core +1 more source
Employment opportunities for non‐coding RNAs [PDF]
FEBS Letters, 2004 Analysis of the genomes of several higher eukaryotic organisms, including mouse and human, has reached the striking conclusion that the mammalian transcriptome is constituted in large part of non‐protein‐coding transcripts. Conversely, the number of protein‐coding genes was initially at least overestimated.
Morey, Céline, Avner, Philip
openaire +2 more sources