Results 41 to 50 of about 894,957 (355)

An improved method for surface immobilisation of RNA: application to small Non-Coding RNA - mRNA pairing [PDF]

, 2013
Characterisation of RNA and its intermolecular interactions is increasing in importance as the inventory of known RNA functions continues to expand. RNA-RNA interactions are central to post-transcriptional gene regulation mechanisms in bacteria, and the ...
Butt, Louise, Callaghan, Anastasia, Gowers, Darren, Henderson, Charlotte, Mardle, C., Phillips, Jack, Pickford, Andy, Roberts, Adam J., Stone, Carlanne, Vincent, H.   +9 more
core   +3 more sources

Non coding RNA and brain [PDF]

BMC Neuroscience, 2006
Abstract Small non coding RNAs are a group of very different RNA molecules, present in virtually all cells, with a wide spectrum of regulatory functions which include RNA modification and regulation of protein synthesis. They have been isolated and characterized in all organisms and tissues, from Archaeobacteria to mammals. In mammalian brain
PRESUTTI, Carlo, ROSATI J, VINCENTI, Sara, NASI S.   +3 more
openaire   +5 more sources

Associating transcription factors and conserved RNA structures with gene regulation in the human brain

Scientific Reports, 2017
Anatomical subdivisions of the human brain can be associated with different neuronal functions. This functional diversification is reflected by differences in gene expression.
Nikolai Hecker, Stefan E. Seemann, Asli Silahtaroglu, Walter L. Ruzzo, Jan Gorodkin   +4 more
doaj   +1 more source

Non-Coding RNAs and Cancer [PDF]

International Journal of Molecular Sciences, 2013
The discovery of the biological relevance of non-coding RNA (ncRNAs) molecules represents one of the most significant advances in contemporary molecular biology. Expression profiling of human tumors, based on the expression of miRNAs and other short or long ncRNAs, has identified signatures associated with diagnosis, staging, progression, prognosis ...
Calore, Federica, Lovat, Francesca, Garofalo, Michela   +2 more
openaire   +2 more sources

Resistance of Klebsiella pneumoniae to Phage hvKpP3 Due to High-Molecular Weight Lipopolysaccharide Synthesis Failure

Microbiology Spectrum, 2023
The spread of multidrug resistant and hypervirulent Klebsiella pneumoniae has recently increased. Phages have been considered alternatives for treating infections caused by tenacious pathogens.
Huaixin Geng, Lingjie Song, Xianggui Yang, Siyu Xing, Rui Wang, Ying Xu, Xu Jia, Guangxin Luan   +7 more
doaj   +1 more source

Integrative analyses of transcriptome sequencing identify novel functional lncRNAs in esophageal squamous cell carcinoma. [PDF]

, 2017
Long non-coding RNAs (lncRNAs) have a critical role in cancer initiation and progression, and thus may mediate oncogenic or tumor suppressing effects, as well as be a new class of cancer therapeutic targets. We performed high-throughput sequencing of RNA
Ai, B, Bai, X-F, Cao, H-H, Feng, C-C, He, J-Z, Huang, G-W, Koeffler, HP, Lei, F, Li, C-Q, Li, E-M, Li, M, Li, S, Li, X, Li, X-C, Liao, L-D, Lin, D-C, Liu, Y-J, Shen, J-H, Tang, Z-D, Wang, L-D, Wang, M-R, Wang, Q-Y, Wang, S-H, Wu, B-L, Wu, J-Y, Wu, Z-Y, Xu, L-Y, Xu, Y-J, Xue, Y-J, Zhang, J, Zhao, J-M, Zheng, C-P, Zhu, Y   +32 more
core   +1 more source

Non-Coding RNAs in Glioma [PDF]

Cancers, 2018
Glioma is the most aggressive brain tumor of the central nervous system. The ability of glioma cells to migrate, rapidly diffuse and invade normal adjacent tissue, their sustained proliferation, and heterogeneity contribute to an overall survival of approximately 15 months for most patients with high grade glioma.
Ryte Rynkeviciene, Julija Simiene, Egle Strainiene, Vaidotas Stankevicius, Jurgita Usinskiene, Edita Miseikyte Kaubriene, Ingrida Meskinyte, Jonas Cicenas, Kestutis Suziedelis   +8 more
openaire   +3 more sources

The role of noncoding RNAs in cancer lipid metabolism

Frontiers in Oncology, 2022
Research on noncoding ribonucleic acids (ncRNAs) is mostly and broadly focused on microRNAs (miRNAs), cyclic RNAs (circRNAs), and long ncRNAs (lncRNAs), which have been confirmed to play important roles in tumor cell proliferation, invasion, and ...
Ye Wang, Ye Wang, Ye Wang, Qian Li, Qian Li, Qian Li, Song Wang, Song Wang, Song Wang, Bi-jun Wang, Yan Jin, Yan Jin, Yan Jin, Hao Hu, Hao Hu, Hao Hu, Qing-sheng Fu, Qing-sheng Fu, Qing-sheng Fu, Jia-wei Wang, Jia-wei Wang, Jia-wei Wang, Qing Wu, Qing Wu, Qing Wu, Long Qian, Long Qian, Long Qian, Ting-ting Cao, Ting-ting Cao, Ting-ting Cao, Ya-bin Xia, Ya-bin Xia, Ya-bin Xia, Xiao-xu Huang, Xiao-xu Huang, Xiao-xu Huang, Li Xu, Li Xu, Li Xu   +39 more
doaj   +1 more source

The non-coding RNA landscape of plasma cell dyscrasias [PDF]

, 2020
Despite substantial advancements have been done in the understanding of the pathogenesis of plasma cell (PC) disorders, these malignancies remain hard-to-treat.
Azab, Kareem A, et al,, Morelli, Eugenio, Rocca, Roberta   +3 more
core   +1 more source

The non-coding landscape of head and neck squamous cell carcinoma. [PDF]

, 2016
Head and neck squamous cell carcinoma (HNSCC) is an aggressive disease marked by frequent recurrence and metastasis and stagnant survival rates. To enhance molecular knowledge of HNSCC and define a non-coding RNA (ncRNA) landscape of the disease, we ...
Grandis, Jennifer R, Hinton, Andrew, Honda, Thomas K, King, Charles C, Korrapati, Avinaash, Ku, Jonjei, Kuo, Selena Z, Lippman, Scott M, Ongkeko, Weg M, Rahimy, Mehran, Saad, Maarouf A, Singh, Pranav, Wang, Xiao Qi, Wang-Rodriguez, Jessica, Xuan, Yinan, Yu, Vicky, Zheng, Hao, Zou, Angela E   +17 more
core   +3 more sources