Results 251 to 260 of about 963,524 (371)

Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi   +13 more
wiley   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq   +4 more
wiley   +1 more source

Deletion of Gtl2 , imprinted non-coding RNA, with its differentially methylated region induces lethal parent-origin-dependent defects in mice [PDF]

open access: bronze, 2009
Nozomi Takahashi   +7 more
openalex   +1 more source

Systematic Comparison of Commercial Uranyl‐Alternative Stains for Negative‐ and Positive‐Staining Transmission Electron Microscopy of Organic Specimens

open access: yesAdvanced Healthcare Materials, EarlyView.
Negative‐ and positive‐staining TEM is essential for rapid nanometer‐resolution characterization of organic specimens ranging from nanoparticles to cells. Uranyl salts are widely used negative‐/positive‐stains but are radioactive and highly toxic to users and the environment.
Vera M. Kissling   +4 more
wiley   +1 more source

膵癌とlong non-coding RNA

open access: yes, 2016
賢至 高橋   +3 more
semanticscholar   +1 more source

Implementing BMP‐7 Chemically Modified RNA for Bone Regeneration with 3D Printable Hyaluronic Acid‐Collagen Granular Gels

open access: yesAdvanced Healthcare Materials, EarlyView.
This study developed 3D‐printable THA‐Col microgels for delivering BMP‐7 cmRNA. The key result is that hMSCs transfected on the biomaterials showed BMP‐7 secretion levels comparable to pre‐transfected hMSCs, therefore introducing a cmRNA‐activated matrix to promote bone healing.
Daphne van der Heide   +7 more
wiley   +1 more source

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