Results 101 to 110 of about 729,139 (268)
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Nestle Action Plan on the Responsible Sourcing of Cocoa from Cote d’Ivoire June 29, 2012 [PDF]
, 2012 This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
Fair Labor Association
core +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
RECIIS, 2009 Biomedical research has undergone changes in the last four decades which have affected the design of new scientific approaches, the study of diseases associated with pathogenic microorganisms and the development of new products and industrial production ...
Márcia de Oliveira Teixeira +2 more
doaj
Intercompartmental communication in senescence
FEBS Open Bio, EarlyView.Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source
Cooperative R&D: Federal Efforts to Promote Industrial Competitiveness [PDF]
, 2006 [Excerpt] In response to the foreign challenge in the global marketplace, the United States Congress has explored ways to stimulate technological advancement in the private sector.
Schacht, Wendy H
core +6 more sources
Cache Placement in Fog-RANs: From Centralized to Distributed Algorithms
, 2017 To deal with the rapid growth of high-speed and/or ultra-low latency data traffic for massive mobile users, fog radio access networks (Fog-RANs) have emerged as a promising architecture for next-generation wireless networks.
Bai, Bo +3 more
core +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Shaping Inclusive Markets: How Funders and Intermediaries can Help Markets Move toward Greater Economic Inclusion [PDF]
, 2017 Positive progress toward worldwide economic inclusion is not only possible, but can also be made more possible. In Shaping Inclusive Markets, we draw lessons from history on how more inclusive markets have been achieved and highlight ways in which ...
Ahmed Irfan +5 more
core