Results 41 to 50 of about 167,208 (259)

NEDD8 Deamidation Inhibits Cullin RING Ligase Dynamics

Frontiers in Immunology, 2021
Cullin-RING ligases (CRLs) are a significant subset of Ubiquitin E3 ligases that regulate multiple cellular substrates involved in innate immunity, cytoskeleton modeling, and cell cycle.
Priyesh Mohanty, Kiran Sankar Chatterjee, Ranabir Das   +2 more
doaj   +1 more source

Some Interesting Features of Non-Covalent Interactions

Croatica Chemica Acta, 2014
Interactions between closed-shell systems exhibit some common features, four of which are par-ticularly strong for beryllium bonds: geometrical distortion, cooperativity, changes in intrinsic reactivity and changes in the magnetic properties of the interacting subunits, which reflect the perturbations of their electron densities through polarization ...
Martín-Sómer, Ana, Montero-Campillo, M. Merced, Mó, Otilia, Yáñez, Manuel, Alkorta, Ibon, Elguero, José   +5 more
openaire   +4 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Covalent polyphenols-proteins interactions in food processing: formation mechanisms, quantification methods, bioactive effects, and applications

Frontiers in Nutrition
Proteins and polyphenols are abundant in the daily diet of humans and their interactions influence, among other things, the texture, flavor, and bioaccessibility of food.
Kangyi Zhang, Kangyi Zhang, Kangyi Zhang, Jinbao Huang, Jinbao Huang, Jinbao Huang, Dongxu Wang, Xiaochun Wan, Yijun Wang, Yijun Wang, Yijun Wang   +10 more
doaj   +1 more source

The World of Non-Covalent Interactions: 2006 [PDF]

Collection of Czechoslovak Chemical Communications, 2006
The review focusses on the fundamental importance of non-covalent interactions in nature by illustrating specific examples from chemistry, physics and the biosciences. Laser spectroscopic methods and both ab initio and molecular modelling procedures used for the study of non-covalent interactions in molecular clusters are briefly outlined.
Pavel Hobza, Rudolf Zahradník, Klaus Müller-Dethlefs   +2 more
openaire   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

QTAIM analysis dataset for non-covalent interactions in furan clusters

Data in Brief, 2022
Furan clusters are very important to understand the dynamics and properties of the furan solvent. They can be used combined with quantum cluster equilibrium theory to theoretically determine the thermodynamics properties of the furan solvent.
Alhadji Malloum, Jeanet Conradie
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Mechanisms of Starch-Polyphenol Interactions, Structural Characterization, and Their Impact on Functional Properties: A review

Shipin gongye ke-ji
Starch, the primary source of carbohydrates in food, plays a crucial role in nutrition and health owing to its digestive properties and functional regulation and has been a subject of extensive research. Recently, researchers have non-covalently combined
Yanchi WANG, Weiyi WANG, Li LIU, Linghao MENG, Yuan MENG, Hanyue GUAN, Ning XU, Ning XIA   +7 more
doaj   +1 more source