Results 51 to 60 of about 167,208 (259)

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Accurate quantum-centric simulations of intermolecular interactions

Communications Physics
Modelling and simulating non-covalent interactions is challenging, as they are inherently weak, dynamic, and system-specific. Common predictive methods often require trading the accuracy for reducing the otherwise cumbersome computational cost.
Danil Kaliakin, Akhil Shajan, Fangchun Liang, Javier Robledo Moreno, Zhen Li, Abhishek Mitra, Mario Motta, Caleb Johnson, Abdullah Ash Saki, Susanta Das, Iskandar Sitdikov, Antonio Mezzacapo, Kenneth M. Merz Jr   +12 more
doaj   +1 more source

Guanidinium and spermidinium decavanadates: as small biomimetic models to understand non-covalent interactions between decavanadate and arginine and lysine side chains in proteins

Frontiers in Chemical Biology
During the last three decades, numerous investigations have been conducted on polyoxidovanadates to treat several illnesses and inhibit enzymes. Numerous decavanadate compounds have been proposed as potential therapies for Diabetes mellitus, Cancer, and ...
Luis F. Paredes-Pérez, Angel Mendoza, Amalia García-García, Laura E. Serrano-De la Rosa, Miguel A. Méndez-Rojas, Francisco J. Melendez, María Eugenia Castro, Enrique González-Vergara   +7 more
doaj   +1 more source

The n → π* interaction: a rapidly emerging non-covalent interaction

Physical Chemistry Chemical Physics, 2015
This perspective describes the current status of a recently discovered non-covalent interaction named as the n → π* interaction, which is very weak and counterintuitive in nature.
Santosh K, Singh, Aloke, Das
openaire   +3 more sources

Synthesis of multimetallic dendrimers through non-covalent interactions [PDF]

Dalton Trans., 2012
Hexa-ammonium functionalized Dendriphos ligands and mono-sulfonate functionalized metal complexes have been used as building blocks for the preparation of multimetallic dendritic assemblies. These metallodendrimers consist of a single metal centre surrounded by an oligocationic shell formed by the coordinated Dendriphos ligands and multiple associated ...
Snelders, D.J.M., Virboul, M.A.N., Kreiter, R., Versluis, C., van Koten, G., Klein Gebbink, R.J.M.   +5 more
openaire   +3 more sources

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Chemistry and crystal engineering

IUCrJ
Recent studies published in the Chemistry and crystal engineering section of IUCrJ emphasize developments both in methodology and techniques as well as the diverse range of classes of compounds being studied and of problems being tackled.
Susan A. Bourne
doaj   +1 more source

Porphyrin Supramolecular Arrays Formed by Weakly Interacting Meso-Functional Groups on Au(111)

Molecules, 2019
The formation of a binary porphyrinic self-assembled system between meso-tetrakis(4-carboxyphenyl) porphyrin (TCPP) and meso-tetrakis(4-dimethyl amino) porphyrin (TDAP) was easily designed through non-covalent interactions in solution and adsorbed on a ...
Esteban Sánchez-Muñoz, José L. Gárate-Morales, Jacinto Sandoval-Lira, Julio M. Hernández-Pérez, Rocío Aguilar-Sánchez   +4 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Synthesis and crystal structure analysis of (3aRS,6RS,7aRS)-N-(4-bromophenyl)-1,6,7,7a-tetrahydro-3a,6-epoxyisoindole-2(3H)-carboselenoamide

Acta Crystallographica Section E: Crystallographic Communications
The asymmetric unit of the title compound, C15H15BrN2OSe, contains two crystallographically independent molecules in which the cyclohexene and pyrrole rings are in boat and envelope conformations, respectively.
Dimitrii M. Shchevnikov, Atash V. Gurbanov, Victor N. Khrustalev, Menberu Mengesha Woldemariam, Tuncer Hökelek, Roman A. Litvinov   +5 more
doaj   +1 more source