Results 61 to 70 of about 12,679,354 (288)

Covalent polyphenols-proteins interactions in food processing: formation mechanisms, quantification methods, bioactive effects, and applications

open access: yesFrontiers in Nutrition
Proteins and polyphenols are abundant in the daily diet of humans and their interactions influence, among other things, the texture, flavor, and bioaccessibility of food.
Kangyi Zhang   +10 more
doaj   +1 more source

NEDD8 Deamidation Inhibits Cullin RING Ligase Dynamics

open access: yesFrontiers in Immunology, 2021
Cullin-RING ligases (CRLs) are a significant subset of Ubiquitin E3 ligases that regulate multiple cellular substrates involved in innate immunity, cytoskeleton modeling, and cell cycle.
Priyesh Mohanty   +2 more
doaj   +1 more source

Some Interesting Features of Non-Covalent Interactions

open access: yesCroatica Chemica Acta, 2014
Interactions between closed-shell systems exhibit some common features, four of which are par-ticularly strong for beryllium bonds: geometrical distortion, cooperativity, changes in intrinsic reactivity and changes in the magnetic properties of the interacting subunits, which reflect the perturbations of their electron densities through polarization ...
Martín-Sómer, Ana   +5 more
openaire   +4 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

QTAIM analysis dataset for non-covalent interactions in furan clusters

open access: yesData in Brief, 2022
Furan clusters are very important to understand the dynamics and properties of the furan solvent. They can be used combined with quantum cluster equilibrium theory to theoretically determine the thermodynamics properties of the furan solvent.
Alhadji Malloum, Jeanet Conradie
doaj   +1 more source

The World of Non-Covalent Interactions: 2006 [PDF]

open access: yesCollection of Czechoslovak Chemical Communications, 2006
The review focusses on the fundamental importance of non-covalent interactions in nature by illustrating specific examples from chemistry, physics and the biosciences. Laser spectroscopic methods and both ab initio and molecular modelling procedures used for the study of non-covalent interactions in molecular clusters are briefly outlined.
Pavel Hobza   +2 more
openaire   +1 more source

Non-Covalent Coatings on Carbon Nanotubes Mediate Photosensitizer Interactions

open access: yes, 2021
Carbon nanotube-based donor-acceptor devices are used in applications ranging from photovoltaics and sensors to environmental remediation. Non-covalent contacts between donor dyes and nanotubes are often used to optimize sensitization and scalability ...
Rahul V. Rao-Pothuraju   +11 more
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Strong self-healing close-loop recyclable vitrimers via complementary dynamic covalent/non-covalent bonding [PDF]

open access: yes
Epoxy vitrimers represent a new class of high-performance sustainable resins because of their desired mechanical and thermally malleable properties. Unfortunately, existing epoxy vitrimers cannot self-heal at room temperature (R.T.) due to the trade-off ...
Zhang, Qi   +8 more
core   +1 more source

Multivalent non-covalent interactions lead to strongest polymer adhesion [PDF]

open access: yes, 2022
Multivalent interactions play a leading role in biological processes such as the inhibition of inflammation or virus internalization. The multivalent interactions show enhanced strength and better selectivity compared to monovalent interactions, but they
Yu, Leixiao   +7 more
core   +1 more source

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