Results 81 to 90 of about 13,171,915 (295)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Synthesis and crystal structure analysis of (3aRS,6RS,7aRS)-N-(4-bromophenyl)-1,6,7,7a-tetrahydro-3a,6-epoxyisoindole-2(3H)-carboselenoamide

open access: yesActa Crystallographica Section E: Crystallographic Communications
The asymmetric unit of the title compound, C15H15BrN2OSe, contains two crystallographically independent molecules in which the cyclohexene and pyrrole rings are in boat and envelope conformations, respectively.
Dimitrii M. Shchevnikov   +5 more
doaj   +1 more source

Porphyrin Supramolecular Arrays Formed by Weakly Interacting Meso-Functional Groups on Au(111)

open access: yesMolecules, 2019
The formation of a binary porphyrinic self-assembled system between meso-tetrakis(4-carboxyphenyl) porphyrin (TCPP) and meso-tetrakis(4-dimethyl amino) porphyrin (TDAP) was easily designed through non-covalent interactions in solution and adsorbed on a ...
Esteban Sánchez-Muñoz   +4 more
doaj   +1 more source

Exploiting non-covalent interactions in novel long alkyl chain appended tertiary phosphine ligands

open access: yes, 2022
Exploiting non-covalent interactions in novel long alkyl chain appended tertiary phosphine ...
Peter DeAth (4266235)
core   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Synthesis and structure of 3-(14H-dibenzo[a,j]xanthen-14-yl)phenyl nicotinate

open access: yesActa Crystallographica Section E: Crystallographic Communications
In the title compound, C33H21NO3, the dihedral angle between the naphthalene units is 10.85 (4)° and the pyran ring adopts a shallow boat conformation. In the crystal, C—H...N and C—H...O hydrogen bonds link the molecules, enclosing R22(16) ring motifs ...
Ekaterina A. Akishina   +6 more
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

Covalent and Non-Covalent Binding Free Energy Calculations for Peptidomimetic Inhibitors of SARS-CoV-2 Main Protease [PDF]

open access: yes, 2020
COVID-19, the disease caused by the newly discovered coronavirus — SARS-CoV-2, has created global health, social, and economic crisis. At the time of writing (November 12, 2020), there are over 50 million confirmed cases and more than 1 million reported ...
Abd Al-Aziz A., Abu-Saleh   +1 more
core   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

Metal-Based Drug–DNA Interactions and Analytical Determination Methods

open access: yesMolecules
DNA structure has many potential places where endogenous compounds and xenobiotics can bind. Therefore, xenobiotics bind along the sites of the nucleic acid with the aim of changing its structure, its genetic message, and, implicitly, its functions ...
Adriana Corina Hangan   +5 more
doaj   +1 more source

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