Results 51 to 60 of about 332,517 (295)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

China's Enduring Grey-Zone Challenge

, 2021
Over the last decade, China’s strategists have devised an imaginative grey-zone approach that leverages perceived fundamental geo-strategic trends to give China a persistent strategic advantage over others.
Layton, Peter
core  

Voltage Frequency Differential Protection Algorithm

Energies
Advancements in new technologies, a reduction in CO2 emissions, and the rising demand for energy are causing a growth in the share of renewable energy sources.
Zdravko Matišić, Tomislav Antić, Juraj Havelka, Tomislav Capuder   +3 more
doaj   +1 more source

Sandia frequency shift parameter selection for multi-inverter systems to eliminate non-detection zone

IET Renewable Power Generation, 2011
Among frequency drift islanding detection methods, Sandia frequency shift (SFS) is considered as one of the most effective methods in detecting islanding conditions for grid connected photovoltaic (PV) inverters. The performance of the SFS method during an islanding condition and its non-detection zone (NDZ) depends to a great extent on its parameters.
H.H. Zeineldin, S. Conti
openaire   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Molecular detection of bioluminescent dinoflagellates in surface waters of the Patagonian Shelf during early austral summer 2008 [PDF]

, 2014
We investigated the distribution of bioluminescent dinoflagellates in the Patagonian Shelf region using “universal” PCR primers for the dinoflagellate luciferase gene.
Martha Valiadi (576318), Valiadi, M., Allen, John T., M. Debora Iglesias-Rodriguez (402203), M Debora Iglesias-Rodriguez, William M Balch, Painter Stuart C., Stuart C Painter, Iglesias-Rodriguez M. Debora, Painter, S.C., Allen John T., William M. Balch (576321), Stuart C. Painter (576319), Martha Valiadi, Painter, Stuart C., Iglesias-Rodriguez, M.D., Balch William M., Allen, J.T., Balch, William M., Valiadi Martha, Valiadi, Martha, Iglesias-Rodriguez, M. Debora, John T Allen, Balch, W.M., John T. Allen (576320)   +24 more
core   +1 more source

An Effective Method for Islanding Detection Based on Variational Mode Decomposition

Electrica, 2019
The present study presents a new islandingdetection method based on variational mode decomposition (VMD). In the method,the VMD transform of the voltage at point of common coupling is calculated, andthen based on the decomposed modes, an islanding ...
Solgun Salimi, Amangaldi Koochaki
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source