Freedom as Non-Domination and Private Law's Autonomy
Law, Ethics and Philosophy, 2023 Leandro Martins Zanitelli
doaj +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Domination and the Arts of Digital Resistance in Social Media Creator Labor
Social Media + SocietyThis article conducts a collaborative qualitative thematic analysis of in-depth interviews with social media content creators ( N = 53) based in and/or originated from the United Kingdom.
Errol Salamon, Rebecca Saunders
doaj +1 more source
Commentary on Nielsen and Landes, 'Fighting Status Inequalities: Non-domination and Non-interference'. [PDF]
Public Health Ethics, 2016 McBride C.
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Fighting Status Inequalities: Non-domination vs Non-interference. [PDF]
Public Health Ethics, 2016 Nielsen ME, Landes X.
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Una reflexión en torno al concepto de libertad como no-dominación en Walzer y Pettit
Enfoques, 2016 Resumen Tomando como pretexto el concepto de libertad como no-dominación acuñado por Philip Pettit en su celebre Republicanismo, este breve artículo discurre mostrando el proyecto walzeriano de una sociedad libre de dominación, en la cual hombres y ...
Josué Gil Soldevilla
doaj