Results 101 to 110 of about 7,116,367 (259)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Non-Domination and Political Liberal Citizenship Education [PDF]
, 2019 According to Philip Pettit, we should understand republican liberty, freedom as ‘non-domination,’ as a ‘supreme political value.’ It is its commitment to freedom as non-domination, Pettit claims, that distinguishes republicanism from various forms of ...
Neufeld, Blain, Blain Neufeld
core +1 more source
Le care entre dépendance et domination: l'intérêt de la théorie néorépublicaine pour penser une [PDF]
Les Ateliers de l’Ethique, 2009 L’éthique du care est confrontée à un problème qui a des allures de paradoxe: bien que sa politisation paraisse nécessaire, l’éthique du care ne semble pas pouvoir trouver en elle-même les ressources suffisantes à la formulation d’une théorie politique ...
Marie Garrau
doaj
Some results on the independence number of connected domination critical graphs
AKCE International Journal of Graphs and Combinatorics, 2018 A k- γ c-critical graph is a graph G with connected domination number γ c (G) = k and γ c (G + u v) < k for any pair of non-adjacent vertices u and v of G . Let ω and α be respectively the clique number and the independence number of a graph.
P. Kaemawichanurat, T. Jiarasuksakun
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Singed Total Domatic Number of a Graph [PDF]
, 2010 The maximum number of functions in a signed total dominating family on G is the signed total domatic number of G. In this paper, some properties related signed total domatic number and signed total domination number of a graph are studied and found the ...
Shailaja S. Shirkol +2 more
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
A STUDY ON NON SPLIT DOMINATION NUMBER
, 2016 The word “mathematics” comes from the Greek word “Mathema” which means science, knowledge or learning; Mthematiko’s means fond of learning. Today, the term refers to specific body of knowledge - the deductive study of quantity, structure, space and ...
K. Nallu Samy +2 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source