Results 91 to 100 of about 10,122,524 (287)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Self-determination as non-domination [PDF]
, 2011 This article conceptualizes self-determination as non-domination, and distinguishes this from the more standard concept of self-determination as noninterference.
Young, Iris Marion
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
The Problem of Domination by Reason and Its Non-Relativistic Solution
Nordic Wittgenstein Review, 2019 This paper outlines a solution to what can be called “the problem of domination by reason”, “conceptual domination” or “clarificatorory injustice”, connected with how a philosopher may appear to be in a position to legitimately coerce, by means of ...
Oskari Kuusela
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Some results on domination in annihilating-ideal graphs of commutative rings [PDF]
Journal of Hyperstructures. Let R be a commutative ring with identity and A(R) be the set of all ideals of R with non-zero annihilators. The annihilating-ideal graph of R is defined as the graph AG(R) with the vertex set A∗(R) = A(R)\{(0)} and two distinct vertices I and J are ...
Reza Taheri
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Remarks on restrained domination and total restrained domination in graphs [PDF]
, 2005 summary:The restrained domination number $\gamma ^r (G)$ and the total restrained domination number $\gamma ^r_t (G)$ of a graph $G$ were introduced recently by various authors as certain variants of the domination number $\gamma (G)$ of $(G)$.
Zelinka, Bohdan
core +1 more source
Some results on the independence number of connected domination critical graphs
AKCE International Journal of Graphs and Combinatorics, 2018 A k- γ c-critical graph is a graph G with connected domination number γ c (G) = k and γ c (G + u v) < k for any pair of non-adjacent vertices u and v of G . Let ω and α be respectively the clique number and the independence number of a graph.
P. Kaemawichanurat, T. Jiarasuksakun
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source