Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Disproof of a Conjecture in the Domination Theory
In [1] C. Barefoot, F. Harary and K. Jones conjectured that for cubic graphs with connectivity three the difference between the domination and independent domination numbers is at most one. We disprove this conjecture and give an exhaustive answer to the
Zverovich, Vadim +3 more
core +1 more source
Inequalities involving independence domination, $f$-domination, connected and total $f$-domination numbers [PDF]
summary:Let $f$ be an integer-valued function defined on the vertex set $V(G)$ of a graph $G$. A subset $D$ of $V(G)$ is an $f$-dominating set if each vertex $x$ outside $D$ is adjacent to at least $f(x)$ vertices in $D$.
Allan, Robert B. +7 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Freedom as Non-domination and Democratic Inclusion [PDF]
According to neo-republicans, democracy is morally justified because it is among the prerequisites for freedom as non-domination. The claim that democracy secures freedom as non-domination needs to explain why democratic procedures contribute to non ...
Beckman, Ludvig, +5 more
core +2 more sources
The ethics of the international monetary system
The ethics of the international monetary system (IMS) can be framed either as a case of background injustice or of structural injustice. Both ideas suggest that due to the background conditions, the interaction of agents, in a context of no rules, can ...
Constanza Guajardo
doaj +1 more source
ON THE DOMINATION NUMBER OF THE SUM ANNIHILATING IDEAL GRAPH OF A COMMUTATIVE RING AND ON THE DOMINATION NUMBER OF ITS COMPLEMENT [PDF]
The rings considered in this article are commutative with identity which are not integral domains. Let R be a ring. The sum annihilating ideal graph of R is an undirected graph whose vertex set is the set of all non-zero annihilating ideals of R and ...
Subramanian Visweswaran, Patat Sarman
doaj +1 more source
Confucian Role-Ethics with Non-Domination: Civil Compliance in Times of Crisis. [PDF]
Kwak JH.
europepmc +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Automorphisms and independent number of single nonzero component graph over a vector space
In this paper, we introduce a graph structure, called the single non-zero component graph Γ(V) ${\Gamma}\left(\mathbb{V}\right)$ , on a finite dimensional vector space V $\mathbb{V}$ .
Xi Wentao +3 more
doaj +1 more source

