Results 61 to 70 of about 6,604 (278)

Self-determination as non-domination [PDF]

open access: yesEthnicities, 2005
This article conceptualizes self-determination as non-domination, and distinguishes this from the more standard concept of self-determination as noninterference. Principles of non-domination imply relationships between self-determining units and the joint regulation of such relationships.
openaire   +4 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Book review: Politics against domination by Ian Shapiro [PDF]

open access: yes, 2016
In Politics against Domination, Ian Shapiro proposes non-domination as the guiding value for justice, argues that it is best supported by democracy and speculates about measures to realise it across borders.
Sager, Alex
core  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Hybridizing Non-dominated Sorting Algorithms: Divide-and-Conquer Meets Best Order Sort

open access: yes, 2017
Many production-grade algorithms benefit from combining an asymptotically efficient algorithm for solving big problem instances, by splitting them into smaller ones, and an asymptotically inefficient algorithm with a very small implementation constant ...
Buzdalov Maxim   +3 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Modern Republicanism and the History of Republics [PDF]

open access: yes, 2011
It is argued that modern characterizations of republican liberty as adhering to a "non-domination" model of liberty are inaccurate for the period of the Italian Renaissance, and that the humanists of the period, aside from Machiavelli, did not see ...
Hankins, James
core   +1 more source

A Radical Revolution in Thought: Frederick Douglass on the Slave’s Perspective on Republican Freedom [PDF]

open access: yes, 2020
While the image of the slave as the antithesis of the freeman is central to republican freedom, it is striking to note that slaves themselves have not contributed to how this condition is understood.
Coffee, Alan M. S. J.
core  

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