Results 91 to 100 of about 771,313 (279)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Essential and Non-Essential Elements in Razor Clams (Solen marginatus, Pulteney, 1799) from the Domitio Littoral in Campania (Southwestern Tyrrhenian Sea, Italy). [PDF]

Toxics, 2022
Esposito M, Canzanella S, Danese A, Pepe A, Gallo P.   +4 more
europepmc   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Essential Trace Element Status of Pregnant Women with Pregnancy Complication History in Benin City, Nigeria

Journal of Applied Sciences and Environmental Management, 2019
Essential trace elements are catalytic substances needed by the human body in small amount. The objective of this study was to determine the serum levels of selected essential trace elements (copper, zinc, iron and selenium) in pregnant women with ...
G.E. Otebhi, H.B. Osadolor
doaj   +1 more source

Temporal Baseline of Essesntial and Non-essential Elements Recorded in Baleen of Western Arctic Bowhead Whale (Balaena mysticetus). [PDF]

Bull Environ Contam Toxicol, 2022
Shore SL, Giarikos DG, Duffy LK, Edwards MR, Hirons AC.   +4 more
europepmc   +1 more source

Essential and non-essential element concentrations in human milk samples and the assessment of infants’ exposure

Scientific Reports
AbstractAs the data concerning element concentrations in human milk (HM) samples and their intake by infants are lacking in Poland, the present study aimed to explore this issue. The material consisted of HM samples obtained from 30 exclusively breastfeeding mothers during 4–6 weeks postpartum. Additionally, to identify the factors that may potentially
Agnieszka Bzikowska-Jura, Aleksandra Maria Wesołowska, Piotr Sobieraj, Nawrocka, Agnieszka, Filipek, Aleksandra, Durkalec, Maciej, Katyńska, Danuta, Jedziniak, Piotr   +7 more
openaire   +3 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Essential, Non-Essential, and Toxic Elements in the Muscle of Meagre (Argyrosomus regius) from the Tagus Estuary (Portugal)

Oceans
Monitoring trace metals in commercially important fish species provides an early warning of anthropogenic contamination and potential risk to consumers. This study semi-quantified and quantified essential, non-essential, and toxic elements in the muscle ...
André F. Jorge, Carla Rodrigues, Bernardo Quintella, Marco Gomes da Silva, Maria João Lança   +4 more
doaj   +1 more source

Secrets Beyond the Basics in Plant Nutrition: The Potential of Titanium, Zirconium, Chromium and Iodine:Mini Review [PDF]

Journal of Soil Sciences and Agricultural Engineering
In the quest to enhance plant nutrition, this review examines the potential roles of titanium (Ti), zirconium (Zr), chromium (Cr), and iodine (I) in plant growth and development.
Dina Ghazi, A. El-Ghamry, Dina Issa, Eman Rashwan   +3 more
doaj   +1 more source