Results 181 to 190 of about 15,618,429 (289)

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Mycorrhizal Fungal Inoculation Reshapes Chemotype, Nutritional Status, and Metabolic Signatures to Enhance Bioactivity in <i>Origanum compactum</i> Benth. [PDF]

Plants (Basel)
Youne Oumnia A, Mounia AY, Kaoutar O, Said R, Mohammed B, Kaddouri H, Najib AM, Bacem M, Abdessamad T, Hanane D, Nazameen H, Khan Y, Lahcen O.   +12 more
europepmc   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Humans: Intertwined with life and the basic elements in the Anthropocene biosphere. [PDF]

Ambio
Folke C, Hattle A, Jørgensen PS, Österblom H, Bjordam T, Bratman G, Lashus C, Normark S, Wang-Erlandsson L, Daily G, Donges J, Galbraith E, Jobbágy E, König A, Milani T, Nyström M, Reyers B, Rocha J, Rockström J, Schill C.   +19 more
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Bioaccessibility of metals in food supplements: protocols and facts. [PDF]

Biometals
Dos Santos Berón T, Bitencourt GR, Picoloto RS, Bolzan RC, Mello PA.   +4 more
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Trophic interactions and stage-specific accumulation of trace elements in the marine parasitic nematode <i>Anisakis simplex</i>. [PDF]

Curr Res Parasitol Vector Borne Dis
Musiol M, Nachev M, Kumas K, Buchmann K, Sures B.   +4 more
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Ionome Dynamics in Grapevine Leaves. [PDF]

Plants (Basel)
Kováčik J, Vydra M, Husáková L, Piroutková M, Dresler S, Dekan M, Duchoň F.   +6 more
europepmc   +1 more source