Results 251 to 260 of about 61,593 (344)

Chemical Profiling, In Silico and In Vitro Studies to Identify Potential CDK2 and mTOR Inhibitor From Selaginella inaequalifolia (Hook. & Grev.) Spring Ethanolic Extracts

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The current study is aimed to reveal the phytoprofile of Selaginella inaequalifolia (Hook. & Grev.) Spring using GC–MS and predict the drug properties, toxicity, biological properties of S. inaequalifolia ethanolic extracts (SiEE) using in silico methods and in vitro toxicity assays, namely, MTT and BSLB assay.
Johnson Marimuthu Alias Antonysamy   +4 more
wiley   +1 more source

Solvent‐Driven Pore Engineering in Coffee‐Derived Activated Hydrochar: Implications for Post‐Combustion CO2 Capture

open access: yesCarbon Energy, EarlyView.
Solvent washing of coffee‐ground hydrochars produces activated carbons with tunable pore sizes while maintaining surface area. Removing non‐polar contaminants enhances microporosity, increasing CO2 uptake by 40%. Moderate pore sizes (9–12 Å) yield optimal CO2:N2 selectivity, whereas smaller pores reduce selectivity due to stronger interactions between ...
Muhammad Irfan Maulana Kusdhany   +4 more
wiley   +1 more source

Novel Bioactive Multifunctional Polyphenols: A Chemo‐Enzymatic Approach

open access: yesChemistry – A European Journal, EarlyView.
One‐step synthesis of complex alkyl oxystilbenin glucosides (6‐47% yield) in alcoholic medium. Switching to ter‐BuOH as solvent afforded δ‐Viniferin diglucoside, with high selectivity and high yield (> 90%), that can be upgraded by enzymatic esterification to alkyl δ‐Viniferin diglucosides.
Amandine L. Flourat   +8 more
wiley   +1 more source

Rational Design Strategies for Stimuli‐Responsive DNAzymes Using Modified and Artificial Nucleotides

open access: yesChemistry – A European Journal, EarlyView.
Activity control of RNA‐cleaving DNAzymes in response to external stimuli has attracted growing interest for applications in DNA‐based diagnostics, therapeutics, and dynamic DNA nanotechnology. This review summarizes rational design strategies for stimuli‐responsive DNAzymes using modified or artificial nucleotides, including split and caged DNAzymes ...
Yusuke Takezawa, Mitsuhiko Shionoya
wiley   +1 more source

A Riboflavin‐Derived Flavinium Salt Mediates Chemoselective Methylation Reactions

open access: yesChemistry – A European Journal, EarlyView.
A two‐component methylation protocol was developed, where the active flavin mediator can be recycled in a single step. Crystallographic data and NMR spectroscopy support the mechanistic proposal, while chemoselective methylation was observed for a broad range of biologically relevant substrates. ABSTRACT Selective methylation is among the most relevant
Tim Langschwager   +3 more
wiley   +1 more source

Mid‐Infrared Spectroscopy and Machine Learning for Chlorogenic Acid Quantification in Coffee

open access: yesChemie Ingenieur Technik, EarlyView.
Chlorogenic acid (CGA) concentration in coffee was predicted using mid‐infrared (MIR) spectroscopy and a machine learning approach. Forty‐four roasting stages (140–220 °C) plus a green coffee control were analyzed. A multilayer perceptron regressor, trained on preprocessed MIR data, outperformed traditional peak analysis, enabling accurate and ...
Deborah Herdt   +6 more
wiley   +1 more source

Inhibition of Insulin Secretion and Increase of Plasma Non-Esterified Fatty Acids Induced by Biotin Deficiency in Osteogenic Disorder Shionogi Rats.

open access: bronze, 1992
Yuji Furukawa   +8 more
openalex   +2 more sources

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