Results 1 to 10 of about 32,250 (213)

Xylitol prevents NEFA-induced insulin resistance in rats [PDF]

open access: yesDiabetologia, 2012
Increased NEFA levels, characteristic of type 2 diabetes mellitus, contribute to skeletal muscle insulin resistance. While NEFA-induced insulin resistance was formerly attributed to decreased glycolysis, it is likely that glucose transport is the rate-limiting defect.
P, Kishore   +7 more
exaly   +3 more sources

Influence of endogenous NEFA on beta cell function in humans [PDF]

open access: yesDiabetologia, 2015
It is a commonly held view that chronically elevated NEFA levels adversely affect insulin secretion and insulin action (lipotoxicity). However, the effect of NEFA on beta cell function has only been explored using acute NEFA elevations. Our aim was to analyse the relationship between endogenous NEFA levels and beta cell function.In 1,267 individuals ...
Eleni Rebelos   +2 more
exaly   +6 more sources

Are we waking up to the effects of NEFA? [PDF]

open access: yesDiabetologia, 2015
NEFA are mobilised from adipose tissues during fasting or stress. Under conditions of acute or chronic NEFA excess, skeletal muscle and hepatic insulin resistance may ensue. Hence, a wealth of literature has focused on the crosstalk between NEFA and glucose in the pathogenesis of insulin resistance.
Jonathan C Jun, Vsevolod Y Polotsky
exaly   +3 more sources

Association of precalving serum NEFA concentrations with postpartum diseases and reproductive performance in multiparous Holstein cows: Cut‐off values

open access: yesVeterinary Medicine and Science, 2023
Background High concentrations of NEFA relative to a defined reference or ‘cut‐point’ values before calving can predict the risk of specific or collective periparturient disease events.
Mehrdad Mohri
exaly   +2 more sources

High Concentrations of Non-Esterified Fatty Acids During Bovine In Vitro Fertilisation Are Detrimental for Spermatozoa Quality and Pre-Implantation Embryo Development [PDF]

open access: yesJournal of Developmental Biology
High non-esterified fatty acids (NEFAs) during negative energy balance in dairy cattle can impair reproduction. While their effects on oocyte maturation and preimplantation embryo development are known, their impact during fertilisation is largely ...
Abdullah F. Idriss   +3 more
doaj   +2 more sources

The introduction of sexually active bucks at different moments of the oestrous cycle does not modify the NEFAs or the IGF-1 concentrations

open access: yesItalian Journal of Animal Science, 2021
Non-esterified fatty acids (NEFAs) and Insulin-like growth factor-I (IGF-1) concentrations are modified after the induction of a "male effect". The present study examined the effect of the introduction of males into a group of females that were ...
Luis Ángel Zarazaga   +2 more
doaj   +1 more source

Biochemical abnormality in the Brown Swiss breed cows affected with ketosis in the perinatal period

open access: yesTheoretical and Applied Veterinary Medicine, 2023
Ketosis is widespread disturbance among dairy cows, causing significant economic losses and requiring further study of its pathogenesis. This particularly applies to less traditional dairy breeds, including the Brown Swiss.
V. H. Yefimov
doaj   +1 more source

Non-Esterified Fatty Acid Induces ER Stress-Mediated Apoptosis via ROS/MAPK Signaling Pathway in Bovine Mammary Epithelial Cells

open access: yesMetabolites, 2022
Elevated concentrations of non-esterified fatty acid (NEFA) induced by negative energy balance (NEB) during the transition period of dairy cows is known to be toxic for multiple bovine cell types.
Yexiao Yan   +4 more
doaj   +1 more source

Rechterlijk Pardon (Pemaafan Hakim) : Suatu Upaya Menuju Sistem Peradilan Pidana Dengan Paradigma Keadilan Restoratif

open access: yesJurnal IUS, 2020
Tulisan ini akan secara spesifik membahas mengenai pengaturan rechterlijk pardon (pemaafan hakim) dalam RKUHP sebagai salah satu bentuk pendekatan keadilan restoratif yang pada prinsipnya mencoba untuk menghindari penjatuhan pidana penjara sejauh hal ...
Nefa Claudia Meliala
doaj   +1 more source

Circulating Non-Esterified Fatty Acids as Biomarkers for Fat Content and Composition in Pigs

open access: yesAnimals, 2021
Circulating non-esterified fatty acids (NEFA) can reflect the composition of dietary fat or adipose tissues depending on the fasting conditions. Therefore, circulating NEFA may be valuable as biomarkers for meat quality traits, such as intramuscular fat ...
Marc Tor   +8 more
doaj   +1 more source

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