Results 11 to 20 of about 32,284 (246)

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan, Yuhong Luo, Nana Yan, Keisuke Hamada, Nan Zhao, Yangliu Xia, Ping Wang, Changdong Zhao, Dan Qi, Shoumei Yang, Lulu Sun, Jie Cai, Qiong Wang, Changtao Jiang, Oksana Gavrilova, Kristopher W. Krausz, Daxesh P. Patel, Xiaoting Yu, Xuan Wu, Haiping Hao, Weiwei Liu, Aijuan Qu, Frank J. Gonzalez   +22 more
wiley   +1 more source

Use of a glycogenic precursor during the prepartum period and its effects upon metabolic indicators and reproductive parameters in dairy cows

Revista Mexicana de Ciencias Pecuarias, 2020
The aim was to evaluate if 1-2 propanodiol plus calcium propionate (glycogenic precursor) supplementation during the transition period in high yielding dairy cows reduces metabolic and reproductive dysfunctions during early lactation.
Carlos Leyva Orasma, Jesús Jaime Benitez-Rivas, Juan Luis Morales Cruz, Cesar Alberto Meza-Herrera, Oscar Ángel-García, Fernando Arellano-Rodríguez, Guadalupe Calderón-Leyva, Dalia Ivette Carrillo-Moreno, Francisco Veliz Deras   +8 more
doaj   +1 more source

The determinants of fasting and post-load non-esterified fatty acids in older adults: The cardiovascular health study

Metabolism Open, 2023
Aim: Non-esterified fatty acids (NEFA) are potential targets for prevention of key cardiometabolic diseases of aging, but their population-level correlates remain uncertain.
Yakubu Bene-Alhasan, David S. Siscovick, Joachim H. Ix, Jorge R. Kizer, Russell Tracy, Luc Djoussé, Kenneth J. Mukamal   +6 more
doaj   +1 more source

Effects of blood sample collection and preparation methods on concentrations of glucose and nonesterified fatty acids in dairy cattle

JDS Communications, 2023
Measurement of concentrations of glucose and nonesterified fatty acids (NEFA) in blood is common in nutrition and physiology studies. Proper collection and preparation conditions of the blood have been less well studied in dairy cattle.
J.K. Drackley
doaj   +1 more source

Genetic Parameter Estimation for Plasma Biomarkers Associated With Energy Reserves During Critical Physiological Stages in Sheep. [PDF]

J Anim Breed Genet
ABSTRACT The ability of ruminants to mobilise and restore body reserves (BR) over time, referred to as BR dynamics, is currently considered an interesting biological component to be included in breeding programs targeting enhanced BR resilience. However, genetic studies of proxies for BR levels and BRD remain scarce, particularly in small ruminants ...
Nyamiel A, Legarra A, Marcon D, Durand C, Douls S, Bonnafe G, Tesnière A, González-García E, Hazard D.   +8 more
europepmc   +2 more sources

Non-esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway

Antioxidants, 2020
Negative energy balance (NEB) during the perinatal period can affect dairy cow follicular development and reduce the fecundity. Non-esterified fatty acid (NEFA) concentration is elevated during NEB, and is known to be toxic for multiple cell types.
Yiru Wang, Chengmin Li, Julang Li, Genlin Wang, Lian Li   +4 more
doaj   +1 more source

In vitro effects of nonesterified fatty acids on bovine neutrophils oxidative burst and viability [PDF]

, 2006
An in vitro study was conducted to examine the influence of nonesterified fatty acids (NEFA) on bovine polymorphonuclear leukocytes (PMN). Eight healthy, midlactating Holstein cows were used as blood donors.
BERNABUCCI, U, Burvenich, Christian, Demeyere, Kristel, Duchateau, Luc, LACETERA, N, SCALIA, D   +5 more
core   +1 more source

Solvent-extracted soybean meal top-dressed on a fresh cow diet increased milk production, but not milk components, and decreased plasma non-esterified fatty acids

Czech Journal of Animal Science, 2019
Post-ruminally infused casein has increased milk and milk protein yield in post-partum cows. We theorised top dressing (TD) higher amounts of soybean meal (SBM) might mimic these effects.
Mohammad Ghelichkhan, Hamid Amanlou, Ehsan Mahjoubi, Robert A. Patton   +3 more
doaj   +1 more source

Increased NEFA levels reduce blood Mg2+ in hypertriacylglycerolaemic states via direct binding of NEFA to Mg2+ [PDF]

Diabetologia, 2018
The blood triacylglycerol level is one of the main determinants of blood Mg2+ concentration in individuals with type 2 diabetes. Hypomagnesaemia (blood Mg2+ concentration 27 kg/m2) who participated in the 300-Obesity study (an observational cross-sectional cohort study, as part of the Human Functional Genetics Projects), we investigated the association
Kurstjens, S, de Baaij, JHF, Overmars-Bos, C, Van Den Munckhof, ICL, Garzero, V, De Vries, MA, Burggraaf, B, Van Diepen, JA, Riksen, NP, Rutten, JHW, Netea, MG, Cabezas, M, Bindels, RJM, Ashcroft, FM, Tack, CJJ, Hoenderop, JGJ   +15 more
openaire   +4 more sources

Effect of high and low glycaemic index recovery diets on intramuscular lipid oxidation during aerobic exercise [PDF]

, 2008
Intramyocellular lipid (IMCL) and plasma NEFA are important skeletal muscle fuel sources. By raising blood insulin concentrations, carbohydrate ingestion inhibits lypolysis and reduces circulating NEFA.
Emma Stevenson, Jennie Brand-Miller, Karola Stockmann, Michael I. Trenell, Stannard, Stevenson   +5 more
core   +1 more source