Preeclampsia is associated with compromized maternal synthesis of long chain polyunsaturated fatty acids leading to offspring deficiency [PDF]
, 2012 Obesity and excessive lipolysis are implicated in preeclampsia (PE). Intrauterine growth restriction is associated with low maternal body mass index and decreased lipolysis.
Brown, E.A. +11 more
core +2 more sources
Lipolysis and ketogenesis in cows in early lactation (review) [PDF]
Acta Agriculturae Serbica, 2018 Peripartal metabolic stress is characterized by increased lipid mobilization, when non-esterified fatty acids (NEFA) are increased, as well as by increased ketogenesis, when the concentration of beta-hydroxybutyrate (BHB) is increased.
Lakić Ivana +6 more
doaj
Effect of Insulin on Rate of Hepatic Uptake of NEFA.
Experimental Biology and Medicine, 1960 SummaryConcentrations of NEFA in plasma of blood obtained from splenic artery, portal and hepatic veins were measured in un-anesthetized dogs together with hepatic plasma flow. Rates of hepatic and non-hepatic splanchnic uptake or output of NEFA were calculated before and after insulin administration. A marked increase in rate of hepatic uptake of NEFA
W C, SHOEMAKER +3 more
openaire +2 more sources
Moderate exercise increases affinity of large very low density lipoproteins for hydrolysis by lipoprotein lipase [PDF]
, 2015 Context: Postprandial triglyceride (TG) concentration is independently associated with cardiovascular disease risk. Exercise reduces postprandial TG concentrations but the mechanisms responsible are unclear.
Bedford, Dorothy K. +5 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao +11 more
wiley +1 more source
Model-Based Quantification of the Systemic Interplay between Glucose and Fatty Acids in the Postprandial State. [PDF]
PLoS ONE, 2015 In metabolic diseases such as Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease, the systemic regulation of postprandial metabolite concentrations is disturbed.
Fianne L P Sips +6 more
doaj +1 more source
Insulin response and changes in composition of non-esterified fatty acids in blood plasma of middle-aged men following isoenergetic fatty and carbohydrate breakfasts [PDF]
, 2000 It was previously shown that a high plasma concentration of non-esterified fatty acids (NEFA) persisted after a fatty breakfast, but not after an isoenergetic carbohydrate breakfast, adversely affecting glucose tolerance.
Carpenter, KLH +5 more
core
Chronic unpredictable stress regulates visceral adipocyte-mediated glucose metabolism and inflammatory circuits in male rats [PDF]
, 2014 Chronic psychological stress is a prominent risk factor involved in the pathogenesis of many complex diseases, including major depression, obesity, and type II diabetes.
Abel +53 more
core +1 more source
Advanced Science, EarlyView.Hepatocellular carcinoma (HCC)‐derived extracellular vesicles (EVs) enrich the metabolic enzyme ATP‐citrate lyase (ACLY). EV‐transferred ACLY enhances palmitate biosynthesis, increases the S‐palmitoylation and stability of multiple immune checkpoint proteins, augments the cellular immunosuppressive activity, and ultimately accelerates the malignant ...
Zhijun Liu +11 more
wiley +1 more source
Advanced Science, EarlyView.We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng +8 more
wiley +1 more source