Results 61 to 70 of about 15,236 (204)

Isorhamnetin Ameliorates Non-Esterified Fatty Acid-Induced Apoptosis, Lipid Accumulation, and Oxidative Stress in Bovine Endometrial Epithelial Cells via Inhibiting the MAPK Signaling Pathway

Antioxidants
High concentrations of non-esterified fatty acids (NEFA) in the blood contribute to various metabolic disorders and are linked to endometritis in dairy cows.
Haimiao Lv, Lijuan Liu, Wenna Zou, Ying Yang, Yuan Li, Shengji Yang, Aixin Liang, Liguo Yang   +7 more
doaj   +1 more source

Semaglutide impacts skeletal muscle to a similar extent as caloric restriction in mice with diet‐induced obesity

The Journal of Physiology, EarlyView.
Abstract figure legend Four weeks of semaglutide treatment causes significant reductions in total body weight, fat mass, lean mass, and grip strength in mice with diet induced obesity. Mice treated with semaglutide lost a greater amount of total body weight and fat mass compared to mice fed fed a calorie matched diet.
S. Jeromson, B. Baranowski, M. Akcan, B. D. Waters, K. Eisner, A. Bellucci, S. Trang, A. Abolhassani, M. A. Tello‐Palencia, A. Schweitzer, B. Stefanska, C. J. Mitchell, David C. Wright   +12 more
wiley   +1 more source

Modified colorimetric ultramicro method for estimating Nefa in serum [PDF]

Journal of Clinical Pathology, 1968
A method is described for the estimation of serum free fatty acids based on the ultramicro method of Novák. The difficulty of obtaining an accurate standard graph has been overcome and the interfering effects of phospholipids have been reduced. The method is simple to perform and gives accurate, precise results in 50 μl samples; it is thus suitable for
openaire   +2 more sources

Sex‐specific metabolic responses to glucagon receptor agonism and modulation of the FGF21‐glucagon axis in female mice

The Journal of Physiology, EarlyView.
Abstract figure legend Therapies targeting the glucagon receptor are being explored for obesity treatment, yet most preclinical studies remain male biased. In this study, Merrild and Johansen et al. show that in diet‐induced obese wild‐type mice a long‐acting glucagon analogue (LA‐Gcg) elicits sexually dimorphic effects on weight loss, food intake ...
Christoffer Merrild, Valdemar Brimnes Ingemann Johansen, Christoffer Clemmensen, Pablo Ranea‐Robles   +3 more
wiley   +1 more source

Glucose and fructose contributions to exogenous carbohydrate oxidation and performance at moderate altitude

The Journal of Physiology, EarlyView.
Abstract figure legend Co‐ingesting fructose with glucose increases exogenous carbohydrate oxidation at sea level, but its effect at altitude is unclear. This study compared glucose–fructose (GLU–FRU), glucose alone (GLU) and placebo during 120 min of running at 70% V̇O2max${{\dot{V}}_{{{{\mathrm{O}}}_2}{\mathrm{max}}}}$ at 2500 m in eight males.
Nicola C. Arjomandkhah, Andy J. King, Alex Griffiths, Roderick F. G. J. King, Douglas, J. Morrison, Thomas Preston, John P. O'Hara   +7 more
wiley   +1 more source

Hormonal Responses to a Short Daytime Fast in Children With Beta‐Oxidation Disorders

JIMD Reports, Volume 67, Issue 5, September 2026.
ABSTRACT Fasting‐induced cellular energy deficiency and hypoglycemia are well‐known complications of beta‐oxidation disorders. The changes in energy homeostasis during fasting are under hormonal regulation. This aspect of fasting metabolism in beta‐oxidation disorders is not fully characterized.
David Olsson, Maria Halldin, Charlotte Bieneck Haglind, Svetlana Lajic, Anna Nordenström   +4 more
wiley   +1 more source

Effect of high NEFA concentration on lipid metabolism disorders in hepatocytes based on lipidomics

Frontiers in Pharmacology
Introduction: High concentrations of nonesterified fatty acids (NEFA) is the key of characteristic of fatty liver in dairy cows. Therefore, the aim of this study was to investigate the effect of high concentration of NEFA on lipid metabolism in ...
Xinyi Fan, Jie Xu, Yuan Hu, Kui Wang, Yiyi Zhao, Jinyin Cai, Xinyuan Zhang, Binghai Pan, Anqi Xu, Yajing Chen, Songhao Liu, Kangfeng Jiang, Xiaobing Li   +12 more
doaj   +1 more source

Lipodystrophy and adipose tissue recovery are mediated by the Wnt/lipogenesis axis during skin fibrosis

The Journal of Pathology, Volume 270, Issue 1, Page 98-113, September 2026.
Abstract Acquired lipodystrophy in the dermal white adipose tissue (DWAT) is an early phenotype of skin fibrosis, followed by the accumulation of extracellular matrix (ECM). Lipodystrophy syndromes are estimated to affect 1 in 20,000 people and are associated with metabolic comorbidities.
Suneeti R Madhavan, Piper Moore, Rohan Varshney, Miles Montegut, Qiannan Ma, Kayla Klatt, Reshmi Parameswaran, Elif G Ertugral, Chandrasekhar R Kothapalli, Michael C Rudolph, Radhika P Atit   +10 more
wiley   +1 more source

PHB2-mediated inhibition of OPA1 cleavage alleviates nonesterified fatty acid–induced apoptosis in bovine mammary epithelial cells

Journal of Dairy Science
: Excessive nonesterified fatty acids (NEFA) during the transition period impose metabolic stress on the bovine mammary gland. High NEFA levels induce oxidative stress and trigger apoptosis in bovine mammary epithelial cells.
Guojin Li, Qi Shao, Qingyan Yin, Kai Liu, Liguang Cao, Jianchun Luo, Depeng Li, Qianwen Sun, Lin Lei, Yuxiang Song, Xiliang Du, Xinwei Li, Guowen Liu, Wenwen Gao   +13 more
doaj   +1 more source

Effect of Guanylic Acid on Plasma NEFA Response to Stress.

Experimental Biology and Medicine, 1960
SummaryPretreatment with hydrocortisone restores plasma NEFA response of adrenalectomized animals to normal but is without effect on intact rats. Pretreatment with guanylic acid, a purine nucleotide, abolishes NEFA response to fasting and tourniquet stress in the normal animal.
J, KABAL, E R, RAMEY
openaire   +2 more sources