Results 81 to 90 of about 32,284 (246)
PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3‐L1 adipocytes
British Journal of Pharmacology, EarlyView.Basal conditions: •Ins/PDE3B lowers cytoplasmic cAMP (cyt‐cAMP) without affecting plasma membrane cAMP (pm‐cAMP). •Insulin decreases lipid droplet cAMP (LD‐cAMP) independent of PDE3B. •FGF1/PDE4D modestly reduces both cyt‐ and pm‐cAMP, while PDE4D alone can modulate LD‐cAMP. ISO stimulation: •Ins/PDE3B has minimal impact on cyt‐cAMP.
Johannes Krier +9 more
wiley +1 more source
Postprandial Glucagon Action in the Human Brain
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims Elevated fasting glucagon is linked to hyperglycemia, but postprandial glucagon effects are less understood. Recent evidence suggests metabolic benefits of rising glucagon after oral glucose intake, potentially impacting brain‐mediated whole‐body metabolism.
Robert Wagner +11 more
wiley +1 more source
Obesity dependent metabolic signatures associated with nonalcoholic fatty liver disease progression [PDF]
, 2012 Our understanding of the mechanisms by which nonalcoholic fatty liver disease (NAFLD) progresses from simple steatosis to steatohepatitis (NASH) is still very limited.
Alonso, C +7 more
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Dietary chia seed (Salvia hispanica L.) rich in a-linolenic acid improves adiposity and normalises hypertriacylglycerolaemia and insulin resistance in dyslipaemic rats [PDF]
, 2009 The present study investigates the benefits of the dietary intake of chia seed (Salvia hispanica L.) rich in α-linolenic acid and fibre upon dyslipidaemia and insulin resistance (IR), induced by intake of a sucrose-rich (62.5 %) diet (SRD).
Chicco, Adriana Graciela +4 more
core +1 more source
Fast & fuelious: the malate–aspartate shuttle in brown adipocyte lipid metabolism
The FEBS Journal, EarlyView.Brown adipose tissue (BAT) produces heat in response to cold exposure, for which it relies on the coordination of aerobic and anaerobic metabolism. However, how reaction intermediates connect these two essential pathways is unclear. In this issue of The FEBS Journal, Veliova et al., report that the malate–aspartate shuttle (MAS) supports norepinephrine‐
Lukas Blaas, Alexander Bartelt
wiley +1 more source
AntioxidantsHigh concentrations of non-esterified fatty acids (NEFA) in the blood contribute to various metabolic disorders and are linked to endometritis in dairy cows.
Haimiao Lv +7 more
doaj +1 more source
Fluid balance and metabolic response in athletic horses fed forage diets [PDF]
, 2009 Concentrate diets are related to health problems in athletic horses and high-energy forage diets could be an alternative. Forage feeding may alter substrate and hindgut fluid availability which could be beneficial during feed deprivation and dehydration.
Connysson, Malin
core
Journal of Animal Physiology and Animal Nutrition, EarlyView.ABSTRACT Inadequate colostrum intake increases risks of calf morbidity and mortality. This study investigated the effects of prepartum and early postpartum supplementation and yeast fermentation products on late‐pregnant Bos indicus cows, and the role of progesterone in mediating passive immunity transfer.
Latino G. S. Coimbra +3 more
wiley +1 more source
Modified colorimetric ultramicro method for estimating Nefa in serum [PDF]
Journal of Clinical Pathology, 1968 A method is described for the estimation of serum free fatty acids based on the ultramicro method of Novák. The difficulty of obtaining an accurate standard graph has been overcome and the interfering effects of phospholipids have been reduced. The method is simple to perform and gives accurate, precise results in 50 μl samples; it is thus suitable for
openaire +2 more sources
Glucocorticoid Receptor and Adipocyte Biology. [PDF]
, 2018 Glucocorticoids are steroid hormones that play a key role in metabolic adaptations during stress, such as fasting and starvation, in order to maintain plasma glucose levels.
Harris, Charles A +2 more
core +2 more sources