Lipolysis generates platelet dysfunction after in vivo heparin administration [PDF]
, 2002 Heparin, when administered to patients undergoing operations using cardiopulmonary bypass, induces plasma changes that gradually impair platelet macroaggregation, but heparinization of whole blood in vitro does not have this effect.
Belcher, P.R. +5 more
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Impact of Heated Versus Unheated Cooking Oil on Postprandial Vascular Function and Metabolism
Lipids, EarlyView.ABSTRACT The impact of repeated heating of seed‐based culinary oils on cardiometabolic health has not been well established. Heating oils to high temperatures (> 150°C) causes lipid peroxidation, thus generating potentially harmful compounds that may impair vascular function. This randomized, single‐blind, crossover study investigated the acute effects
Rosiered Brownson‐Smith +5 more
wiley +1 more source
Hyperinsulinism in short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of beta-oxidation in insulin secretion [PDF]
, 2001 A female infant of nonconsanguineous Indian parents presented at 4 months with a hypoglycemic convulsion. Further episodes of hypoketotic hypoglycemia were associated with inappropriately elevated plasma insulin concentrations.
Aynsley-Green, A +9 more
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Hypothesis: ‘Vasocrine’ signalling from perivascular fat - a mechanism linking insulin resistance and vascular disease [PDF]
, 2005 Adipose tissue expresses cytokines which inhibit insulin signalling pathways in liver and muscle. Obesity also results in impairment of endothelium-dependent vasodilatation to insulin. We propose a vasoregulatory role for local deposits of fat around the
Eringa, E. +2 more
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Obesity, EarlyView.This study identifies G protein‐coupled receptor 17 (Gpr17) as a novel regulator of leptin and insulin sensitivity. Using complementary knockout models, we demonstrate that Gpr17 deletion enhances energy expenditure, restores leptin responsiveness, and improves insulin sensitivity, revealing Gpr17 as a potential therapeutic GPCR target for obesity and ...
Xun Sun +8 more
wiley +1 more source
Differences in the serum nonesterified Fatty Acid profile of young women associated with a recent history of gestational diabetes and overweight/obesity. [PDF]
PLoS ONE, 2015 Nonesterified fatty acids (NEFA) play pathophysiological roles in metabolic syndrome and type 2 diabetes (T2D). In this study, we analyzed the fasting NEFA profiles of normoglycemic individuals at risk for T2D (women with a recent history of gestational ...
Marina Fugmann +9 more
doaj +1 more source
Maternal obesity is associated with the formation of small dense LDL and hypoadiponectinemia in the third trimester [PDF]
, 2013 Context: Maternal obesity is associated with high plasma triglyceride, poor vascular function, and an increased risk for pregnancy complications. In normal-weight pregnant women, higher triglyceride is associated with increased small, dense low-density ...
Brown, E.A. +9 more
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The paradox of mosquito net fishing: Complex socio‐ecological trade‐offs in southwestern Madagascar
People and Nature, EarlyView.Abstract Small‐scale fisheries are vital for the livelihoods, nutrition and well‐being of millions of people in coastal regions. In many parts of the Global South, rising poverty, limited alternatives and declining resources have driven the spread of mosquito net fishing (MNF), a non‐selective practice using repurposed health‐distributed nets.
Francéline Marie Rasoanirina +6 more
wiley +1 more source
ADMINISTRATION OF EARLY POST-PARTUM ORAL DRENCH IN DAIRY COWS: EFFECTON METABOLIC PROFILE
Revista de la Facultad de Medicina Veterinaria y de Zootecnia, 2015 Some prophylactic treatments have been proposed in high-yielding dairy cattle in order to minimize the effects of negative energy balance and some disturbances such as hypocalcaemia and ketosis.
R. Schallenberger Gonçalves +4 more
doaj
Insulin Regulates Lipolysis and Fat Mass by Upregulating Growth/Differentiation Factor 3 in Adipose Tissue Macrophages [PDF]
, 2019 学位記番号 ...
Bu, Yun, ブ, イュン, 歩, 云
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