Results 71 to 80 of about 19,678 (222)

Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Older Individuals.

, 2017
Introduction. The mechanisms underlying the association between insulin resistance and intrahepatic lipid (IHL) accumulation are not completely understood.
Hatunic, Mensud, Sleigh, Alison, Cooper, Cyrus, Griffin, Simon J., Finucane, Francis M., Sharp, Stephen J., De Lucia Rolfe, Ema, Wareham, Nicholas J., Sayer, Avan Aihie, Savage, David B.   +9 more
core   +1 more source

Fast & fuelious: the malate–aspartate shuttle in brown adipocyte lipid metabolism

The FEBS Journal, EarlyView.
Brown adipose tissue (BAT) produces heat in response to cold exposure, for which it relies on the coordination of aerobic and anaerobic metabolism. However, how reaction intermediates connect these two essential pathways is unclear. In this issue of The FEBS Journal, Veliova et al., report that the malate–aspartate shuttle (MAS) supports norepinephrine‐
Lukas Blaas, Alexander Bartelt
wiley   +1 more source

Effects of Prepartum Supplementation and Yeast Fermentation Products on the Progesterone‐Modulated Transfer of Passive Immunity in Bos indicus Cows

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Inadequate colostrum intake increases risks of calf morbidity and mortality. This study investigated the effects of prepartum and early postpartum supplementation and yeast fermentation products on late‐pregnant Bos indicus cows, and the role of progesterone in mediating passive immunity transfer.
Latino G. S. Coimbra, Fran C. Cowley, Geoffry Fordyce, Luis F. P. Silva   +3 more
wiley   +1 more source

Isorhamnetin Ameliorates Non-Esterified Fatty Acid-Induced Apoptosis, Lipid Accumulation, and Oxidative Stress in Bovine Endometrial Epithelial Cells via Inhibiting the MAPK Signaling Pathway

Antioxidants
High concentrations of non-esterified fatty acids (NEFA) in the blood contribute to various metabolic disorders and are linked to endometritis in dairy cows.
Haimiao Lv, Lijuan Liu, Wenna Zou, Ying Yang, Yuan Li, Shengji Yang, Aixin Liang, Liguo Yang   +7 more
doaj   +1 more source

Sleep Improvement for Metabolic Health: A Feasibility Trial of a Digital Sleep Treatment in People With Insomnia and Non‐Diabetic Hyperglycaemia

Journal of Sleep Research, EarlyView.
ABSTRACT Insomnia may play a causal role in type 2 diabetes (T2D). Addressing insomnia through cognitive behavioural therapy (CBTi) in people with non‐diabetic hyperglycaemia could potentially reduce the risk of progression to T2D. To inform a future randomised trial, we performed a feasibility study of digital CBT (dCBTi) in individuals at increased ...
Rachel Sharman, David Ray, Andrew Farmer, Poppy C. E. Green, Victoria Harris, Fredrik Karpe, Colin A. Espie, Diana Mantripp, Thomas Marjot, Niall M. McGowan, Jeremy W. Tomlinson, Simon D. Kyle   +11 more
wiley   +1 more source

Differential Pathophysiological Drivers of Susceptibility to Type 2 Diabetes and Metabolic Dysfunction–Associated Steatotic Liver Disease: Ethnic Differences in Insulin Dynamics, Whole‐Body Fat Metabolism, and Organ‐Specific Lipid Deposition

Obesity Reviews, EarlyView.
ABSTRACT Introduction This narrative review explores the epidemiological evidence and potential underlying pathophysiological defects underlying the disproportionately greater risk of Type 2 diabetes (T2D) and cardiometabolic disease in people of South Asian and African Caribbean ancestry compared with White Europeans.
Daniel J. Cuthbertson, Martin Whyte, Alex E. Henney, Uazman Alam, Louise Goff, Barbara A. Fielding, A. Margot Umpleby   +6 more
wiley   +1 more source

Modified colorimetric ultramicro method for estimating Nefa in serum [PDF]

Journal of Clinical Pathology, 1968
A method is described for the estimation of serum free fatty acids based on the ultramicro method of Novák. The difficulty of obtaining an accurate standard graph has been overcome and the interfering effects of phospholipids have been reduced. The method is simple to perform and gives accurate, precise results in 50 μl samples; it is thus suitable for
openaire   +2 more sources

Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity

Obesity Reviews, EarlyView.
ABSTRACT Excess adiposity is not a recently developed problem but has existed since at least the upper Paleolithic, allowing evolutionary selection pressures to adapt the physiology of the pregnant woman and the feto‐placental unit for maternal and fetal protection.
Gernot Desoye, Ursula Hiden, Evelyn Jantscher‐Krenn, Herbert Fluhr, Jonathan C. Wells, Sonja Entringer, Mireille N. M. van Poppel   +6 more
wiley   +1 more source

NEFA-species in rat liver and rat serum.

, 2014
A NEFA-species in rat liver homocysteine in rat serum; B NEFA-species in rat serum. The control group is shown as black bar, the fructose-fed group is shown as red bar and the FF treated group is shown as a blue bar; values given are means±s.d ...
Mark Broenstrup (627128), Tatiana Konovalova (548743), Hans-Ludwig Schaefer (627126), Gerd Schmitz (44452), Martin Troetzmueller (627127), Thomas Kopf (548745), Harald Koefeler (440003)   +6 more
core   +1 more source

Co‐ingesting whey protein with dual‐source carbohydrate enhances amino acid availability without compromising post‐exercise liver glycogen resynthesis

The Journal of Physiology, EarlyView.
Abstract figure legend Graphical overview of the experimental study. The upper‐left panel presents the research question, and the bottom‐left panel provides a schematic overview of the experimental design. The right‐hand panel depicts repetitive spectral data obtained by magnetic resonance spectroscopy, liver glycogen content during the 5 h post ...
Sophie C. Hannon, James McStravick, Libby Henthorn, Stephen J. Bawden, Jonathan C. Y. Tang, Rachel Dunn, Ryosuke Makino, Kenneth Smith, Javier T. Gonzalez, Nathan Hodson, James P. Morton, Aneurin J. Kennerley, Mark A. Hearris   +12 more
wiley   +1 more source