Results 91 to 100 of about 32,284 (246)

Sleep Improvement for Metabolic Health: A Feasibility Trial of a Digital Sleep Treatment in People With Insomnia and Non‐Diabetic Hyperglycaemia

Journal of Sleep Research, EarlyView.
ABSTRACT Insomnia may play a causal role in type 2 diabetes (T2D). Addressing insomnia through cognitive behavioural therapy (CBTi) in people with non‐diabetic hyperglycaemia could potentially reduce the risk of progression to T2D. To inform a future randomised trial, we performed a feasibility study of digital CBT (dCBTi) in individuals at increased ...
Rachel Sharman, David Ray, Andrew Farmer, Poppy C. E. Green, Victoria Harris, Fredrik Karpe, Colin A. Espie, Diana Mantripp, Thomas Marjot, Niall M. McGowan, Jeremy W. Tomlinson, Simon D. Kyle   +11 more
wiley   +1 more source

Effects of hirudin-induced activation of nonenzymatic fibrinolysis during immobilization stress [PDF]

The specific inhibitor of thrombin, hirudin, was used for studying the mechanism of the activating effect of ACTH and adrenalin on nonenzymatic fibrinolytic activity (NEFA), the latter characterizing the function of the anticoagulation system (ACS ...
Baskova, I. P., Cherkesova, L. U., Goldovskaya, M. D., Lyapina, L. A., Shapiro, F. B.   +4 more
core   +1 more source

A forage-only diet alters the metabolic response of horses in training [PDF]

, 2012
Most athletic horses are fed a high-starch diet despite the risk of health problems. Replacing starch concentrate with high-energy forage would alleviate these health problems, but could result in a shift in major substrates for muscle energy supply from
A. Jansson, Connysson, Connysson, Danielsen, Devlin, Ellis, Essén-Gustavsson, Essén-Gustavsson, Farris, Geor, Gillham, Glade, Harris, Hintz, Houpt, Hudson, Hyyppä, J.E. Lindberg, Kelso, Lacombe, Lacombe, Lawrence, Lindholm, Lowry, Luthersson, MacLeay, Meyer, Muhonen, Pagan, Palmgren-Karlsson, Palmgren-Karlsson, Persson, Potter, Ragnarsson, Redbo, Schuback, Snow, Tinker, Voiton, Waller, Waller, Waters, Willard, Williamson, Willing, Wilson   +45 more
core   +2 more sources

Differential Pathophysiological Drivers of Susceptibility to Type 2 Diabetes and Metabolic Dysfunction–Associated Steatotic Liver Disease: Ethnic Differences in Insulin Dynamics, Whole‐Body Fat Metabolism, and Organ‐Specific Lipid Deposition

Obesity Reviews, EarlyView.
ABSTRACT Introduction This narrative review explores the epidemiological evidence and potential underlying pathophysiological defects underlying the disproportionately greater risk of Type 2 diabetes (T2D) and cardiometabolic disease in people of South Asian and African Caribbean ancestry compared with White Europeans.
Daniel J. Cuthbertson, Martin Whyte, Alex E. Henney, Uazman Alam, Louise Goff, Barbara A. Fielding, A. Margot Umpleby   +6 more
wiley   +1 more source

Effect of high NEFA concentration on lipid metabolism disorders in hepatocytes based on lipidomics

Frontiers in Pharmacology
Introduction: High concentrations of nonesterified fatty acids (NEFA) is the key of characteristic of fatty liver in dairy cows. Therefore, the aim of this study was to investigate the effect of high concentration of NEFA on lipid metabolism in ...
Xinyi Fan, Jie Xu, Yuan Hu, Kui Wang, Yiyi Zhao, Jinyin Cai, Xinyuan Zhang, Binghai Pan, Anqi Xu, Yajing Chen, Songhao Liu, Kangfeng Jiang, Xiaobing Li   +12 more
doaj   +1 more source

Al-Qaeda in Gaza: isolating “the base” [PDF]

, 2010
In 1996, Osama bin Laden declared jihad against the American forces occupying Saudi Arabia, calling for Muslims to expel the infidels from the “land of the two holy places.” The first sacred ground mentioned in this statement, however, was not Saudi ...
Marshall, Warren
core   +1 more source

Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity

Obesity Reviews, EarlyView.
ABSTRACT Excess adiposity is not a recently developed problem but has existed since at least the upper Paleolithic, allowing evolutionary selection pressures to adapt the physiology of the pregnant woman and the feto‐placental unit for maternal and fetal protection.
Gernot Desoye, Ursula Hiden, Evelyn Jantscher‐Krenn, Herbert Fluhr, Jonathan C. Wells, Sonja Entringer, Mireille N. M. van Poppel   +6 more
wiley   +1 more source

Effects of maternal subnutrition during early pregnancy on cow hematological profiles and offspring physiology and vitality in two beef breeds [PDF]

, 2019
This experiment evaluated the effects of subnutrition during early gestation on hematology in cows (Bos Taurus) and on hematological, metabolic, endocrine, and vitality parameters in their calves.
Almaguer C., Civelek T., Fay R. A., García‐Belenguer S., Krimer P. M., Lozano M., Schafer S., Schultz R. D., Tchernia G., Tennant B.   +9 more
core   +2 more sources

Co‐ingesting whey protein with dual‐source carbohydrate enhances amino acid availability without compromising post‐exercise liver glycogen resynthesis

The Journal of Physiology, EarlyView.
Abstract figure legend Graphical overview of the experimental study. The upper‐left panel presents the research question, and the bottom‐left panel provides a schematic overview of the experimental design. The right‐hand panel depicts repetitive spectral data obtained by magnetic resonance spectroscopy, liver glycogen content during the 5 h post ...
Sophie C. Hannon, James McStravick, Libby Henthorn, Stephen J. Bawden, Jonathan C. Y. Tang, Rachel Dunn, Ryosuke Makino, Kenneth Smith, Javier T. Gonzalez, Nathan Hodson, James P. Morton, Aneurin J. Kennerley, Mark A. Hearris   +12 more
wiley   +1 more source

PHB2-mediated inhibition of OPA1 cleavage alleviates nonesterified fatty acid–induced apoptosis in bovine mammary epithelial cells

Journal of Dairy Science
: Excessive nonesterified fatty acids (NEFA) during the transition period impose metabolic stress on the bovine mammary gland. High NEFA levels induce oxidative stress and trigger apoptosis in bovine mammary epithelial cells.
Guojin Li, Qi Shao, Qingyan Yin, Kai Liu, Liguang Cao, Jianchun Luo, Depeng Li, Qianwen Sun, Lin Lei, Yuxiang Song, Xiliang Du, Xinwei Li, Guowen Liu, Wenwen Gao   +13 more
doaj   +1 more source