Results 201 to 210 of about 17,406,766 (301)

A comprehensive evaluation of the human Tg32 and Tg276 FcRn transgenic mouse and non-human primate models for predicting antibody pharmacokinetics in human. [PDF]

MAbs
Gajewska M, Kiffe M, Calonder C, Engelhardt V, Pou I Miralbell C, Gonzalo-Gil E, Christianson G, Bethur N, Flora A.   +8 more
europepmc   +1 more source

Species traits mediate terrestrial mammal density responses to human impacts

Ecography, EarlyView.
Human activities are reshaping ecosystems, but their effects on species population density remain poorly understood. Most studies focus on species presence–absence, thus limiting insight into how anthropogenic pressures affect population density. Emerging evidence suggests that responses of natural populations to human disturbance are highly variable ...
Luca Santini, Diana E. Bowler, Roberto Salguero‐Gómez, Inês S. Martins, Franziska Schrodt, Romain Frelat, Mickael Hedde, Naia Morueta‐Holme, Pierre Gaüzère, Cyrille Violle, Romain Goury, Joaquim Estopinan, Miriam Beck, Wilfried Thuiller   +13 more
wiley   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Learning a refinement model for variant analysis in non-human primate genomes. [PDF]

BMC Genomics
Choi J, Zhou B, Song G.
europepmc   +1 more source

Reflex seizures and epilepsy surgery: A network approach case‐based exploration

Epileptic Disorders, EarlyView.
Abstract Context Reflex seizures (RS) are defined by their consistent provocation by specific stimuli, encompassing a broad range from elementary sensory inputs to complex cognitive tasks. While RS are often encountered in clinical practice, their surgical management remains sparsely reported and poorly systematized.
Olivier Aron, Laure Salmon, Nicolas Nguyen, Dènahin Toffa, Sami Obaid, Alexis Robin, Dang Khoa Nguyen   +6 more
wiley   +1 more source

Correction: Non-human primate preclinical model revealed the feasibility and short-term safety of iPSC-derived innate-like T cells in autologous transplantation. [PDF]

Front Immunol
Miyake Y, Iriguchi S, Kawana-Tachikawa A, Kitayama S, Imai E, Taya K, Ishii H, Miura T, Sakawaki H, Matano T, Kaneko S.   +10 more
europepmc   +1 more source

Direct cortical stimulation–evoked symptoms in the human temporal pole: A systematic review

Epileptic Disorders, EarlyView.
Abstract The temporal pole represents a key node within temporolimbic networks and may contribute to seizure generation in temporal lobe epilepsy. Direct cortical stimulation (DCS), performed during intracranial presurgical evaluation, is a valuable method for delineating the seizure onset zone by reproducing electro‐clinical features of a patient's ...
Yulia Novitskaya, Andreas Schulze‐Bonhage   +1 more
wiley   +1 more source

Development of a non-human primate model for preclinical research of a novel auditory nerve implant. [PDF]

Front Neurosci
Sondh I, Johnson LA, Ghose GM, Loveland A, Larson L, Lim HH, Adams ME.   +6 more
europepmc   +1 more source

Theta oscillations, epileptogenesis, and focal seizures in rodent models of mesial temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Theta oscillations (4–12 Hz) are a prominent network rhythm within hippocampal and parahippocampal structures. Driven by cholinergic and γ‐aminobutyric acidergic inputs originating from the medial septum, physiological theta gates network excitability to control spatial navigation, memory encoding, and sensorimotor integration during specific ...
Maxime Lévesque, Massimo Avoli
wiley   +1 more source

Identification and Phylogenetic Characterisation of Novel Adeno-Associated Virus Capsids in Non-Human Primate Tissues. [PDF]

Cell Prolif
Zhu L, Xu K, Ding Y, Liu K, Liu J, Hou Z, Niu R, Yang N, Qin H, Hu B, Zhang Y, Li W.   +11 more
europepmc   +1 more source