Results 211 to 220 of about 237,923 (376)

Engineered Exosome‐Based Senolytic Therapy Alleviates Stroke by Targeting p21+CD86+ Microglia

Exploration, EarlyView.
We identified a harmful immune cell type, p21+CD86+ microglia, driving post‐stroke inflammation and developed a targeted exosome‐based therapy (Que@micro‐Exo) to eliminate these cells. This innovative treatment reduced inflammation, alleviated brain damage, and improved recovery in stroke models, offering a promising strategy for stroke and other ...
Jialei Yang, Shipo Wu, Miao He
wiley   +1 more source

Non-human primate: the new frontier model of female reproductive engineering. [PDF]

Front Bioeng Biotechnol
Kim YY, Kwak J, Kang BC, Ku SY.
europepmc   +1 more source

Derivation of insulin-producing cells from non-human primate embryonic stem (ES) cells [PDF]

, 2002
Hung‐Chih Kuo, Brian Nauert, Linda B. Lester, Don P. Wolf   +3 more
openalex   +1 more source

Alpha‐Lipoic Acid Alleviates Isoflurane‐Induced Cognitive Dysfunction in Juvenile Mice by Activating Peroxisome Proliferator Activated Receptor Gamma Coactivator ‐1 Alpha

Food Frontiers, EarlyView.
Alpha‐lipoic acid (ALA) plays a significant role in alleviating isoflurane‐induced cognitive dysfunction in juvenile mice by activating PGC‐1α, which improves mitochondrial function and energy metabolism in astrocytes. As a potent antioxidant, ALA is commonly found in foods like spinach, broccoli, and yeast, and its supplementation may offer ...
Xingkai Zhao, Donglu Wang, Shuai Li, Xueting Zhang, Zhenlei Zhou   +4 more
wiley   +1 more source

Immunogenicity and safety of Mycobacterium tuberculosis culture filtrate proteins in non-human primates

, 2000
Roberta Attanasio, K Pehler, Harold M. McClure   +2 more
openalex   +2 more sources

Observations Of Non-Human Primate Diarrhea Viruses By Negative Stain Electron Microscopy [PDF]

, 2002
Charles D. Humphrey, Baoming Jiang, Harold M. McClure   +2 more
openalex   +1 more source

Oligodendrogenesis in Evolution, Development and Adulthood

Glia, EarlyView.
Oligodendrocytes and myelin took shape in jawed vertebrates. During development, OPCs are originated from NSCs and then undergo differentiation into mature oligodendrocytes that supply myelin. OPCs persist in the adult CNS and continue to produce oligodendrocytes and myelin. Adaptive myelination, which fine‐tunes neural circuits in response to neuronal
Hao Hu, Tianhao Gao, Jingwei Zhao, Huiliang Li   +3 more
wiley   +1 more source

Pre-clinical xenotransplantation: physiology and pharmacy in human decedent and non-human primate models. [PDF]

Front Transplant
Anderson DJ, Locke JE.
europepmc   +1 more source

MORPHOLOGIC AND FUNCTIONAL CHARACTERIZATION OF CHAGASIC HEART DISEASE IN NON-HUMAN PRIMATES [PDF]

, 2003
Miguel Zabalgoitia, John L. VandeBerg, K. Dee Carey, Jeff T. Williams, Lori Anderson, Jaime Ventura   +5 more
openalex   +1 more source

What Does Iron Mean to an Oligodendrocyte?

Glia, EarlyView.
ABSTRACT Iron is essential for life and plays a key role in multiple fundamental cellular functions. The brain has the highest rate of energy consumption, and within the brain, oligodendrocytes have the highest level of oxidative metabolism per volume. Oligodendrocytes also stain the strongest for iron.
Quinn W. Wade, James R. Connor
wiley   +1 more source