Results 231 to 240 of about 17,406,766 (301)

Shikonin Promotes Apoptosis in Multiple Myeloma Cells Through the PKM2‐AMPK‐PGC1α Metabolic Axis

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
High PKM2 expression in MM is associated with a poor prognosis. Shikonin represents a promising PKM2‐targeted agent for MM therapy, offering a unique metabolic intervention strategy to improve drug resistance, bone disease, and the immune microenvironment. ABSTRACT Background Multiple myeloma (MM) is an incurable plasma malignancy.
Fengping Peng   +7 more
wiley   +1 more source

Peri‐implant disease pathogenesis animal models: Consensus report of Workgroup 1 of the IADR Implantology Research Group Best Evidence Consensus Symposium on Peri‐Implant Disease and Its Treatment

open access: yesJournal of Periodontology, EarlyView.
Abstract Background The pathogenesis and etiology of peri‐implantitis demand a deeper understanding to lead to successful treatment modalities. Animal models of peri‐implantitis pathogenesis offer unique insights but their translational impact requires consideration of implant biomaterials science.
Georgios Kotsakis   +15 more
wiley   +1 more source

The human and non-human primate developmental GTEx projects. [PDF]

open access: yesNature
Coorens THH   +7 more
europepmc   +1 more source

Position paper: leveraging non-human primate (NHP) specificities to accelerate Parkinson's disease and ageing research. [PDF]

open access: yesNPJ Parkinsons Dis
Bezard E   +15 more
europepmc   +1 more source

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