Shikonin Promotes Apoptosis in Multiple Myeloma Cells Through the PKM2‐AMPK‐PGC1α Metabolic Axis
High PKM2 expression in MM is associated with a poor prognosis. Shikonin represents a promising PKM2‐targeted agent for MM therapy, offering a unique metabolic intervention strategy to improve drug resistance, bone disease, and the immune microenvironment. ABSTRACT Background Multiple myeloma (MM) is an incurable plasma malignancy.
Fengping Peng +7 more
wiley +1 more source
Abstract Background The pathogenesis and etiology of peri‐implantitis demand a deeper understanding to lead to successful treatment modalities. Animal models of peri‐implantitis pathogenesis offer unique insights but their translational impact requires consideration of implant biomaterials science.
Georgios Kotsakis +15 more
wiley +1 more source
A new <i>Oxyspirura</i> (Nematoda, Thelaziidae) in three captive non-human primate species. [PDF]
Máca O, González-Solís D.
europepmc +1 more source
The human and non-human primate developmental GTEx projects. [PDF]
Coorens THH +7 more
europepmc +1 more source
Arterial and venous flow dynamics are modified by age in the non-human primate. [PDF]
Arribarat G +3 more
europepmc +1 more source
Position paper: leveraging non-human primate (NHP) specificities to accelerate Parkinson's disease and ageing research. [PDF]
Bezard E +15 more
europepmc +1 more source
Mozambique's Colonial-Era Non-Human Primate Collection at the National Museum of Natural History and Science of Lisbon: Taxonomy, Provenance, and Historical Context. [PDF]
Osório M, Veracini C.
europepmc +1 more source
The Common Marmoset as a Novel Non-human Primate Model for Inner Ear Research. [PDF]
Hosoya M.
europepmc +1 more source
A Combination Strategy for MASH: ACLY Inhibition Paired With PPARα Agonism
iNew Medicine, EarlyView.
Dongdong Wang
wiley +1 more source

