Results 221 to 230 of about 120,353 (299)

Additional file 4: of Proteomics in non-human primates: utilizing RNA-Seq data to improve protein identification by mass spectrometry in vervet monkeys

, 2017
J. Michael Proffitt, Jeremy P. Glenn, Anthony J. Cesnik, Avinash Jadhav, Michael R. Shortreed, Lloyd M. Smith, Kylie Kavanagh, Laura A. Cox, Michael Olivier   +8 more
openalex   +1 more source

Biomarkers of Drug‐Induced Kidney Injury: Use in Clinical Trials and Recent Examples of Impact on Drug Development

Clinical Pharmacology &Therapeutics, EarlyView.
This manuscript describes the scope of implementation and impact of a regulatory agency‐qualified panel of six urine biomarkers on drug development, the process for which was conducted and funded by the Critical Path Institute, the Foundation for the National Institutes of Health, and the United States Food and Drug Administration.
Tanja S. Zabka, Michael Lawton, Tom Chu, Gary S. Friedman, Katrina Peron, Stefan R. Sultana, Warren E. Glaab, Nicholas M. P. King   +7 more
wiley   +1 more source

Advancing non-human primate welfare: An automated facial recognition system for unrestrained cynomolgus monkeys. [PDF]

PLoS One
Numata Y, Sumali B, Hayashida K, Tsusaki H, Mitsukura Y.   +4 more
europepmc   +1 more source

Whole-blood RNA biomarkers for predicting survival in non-human primates following thoracic radiation [PDF]

Molykutty J. Aryankalayil, H. S. Patel, Jared M. May, Uma Shankavaram, Michelle A. Bylicky, Shannon Martello, Sunita Chopra, Jim Axtelle, Naresh Menon, C. Norman Coleman   +9 more
openalex   +1 more source

Pediatric Developmental Safety Assessment: Are We Ready for the Next Thalidomide?

Clinical Pharmacology &Therapeutics, EarlyView.
Pediatric drug development has achieved remarkable success in the last 20 years with over 1,000 products studied in pediatric patients. This success has been driven in part by an increased understanding of pediatric disease processes. The aspect that has been largely overlooked is the potential adverse effect of new drugs on pediatric developmental ...
Gilbert J. Burckart, Susan M. Abdel‐Rahman, Gelareh Abulwerdi, Sherbet Samuels, Rebecca Racz, Mohamed A. Mohamoud, Nicholas P. Tatonetti   +6 more
wiley   +1 more source

Draft genome sequence of a non-human primate-derived isolate of Candida parapsilosis. [PDF]

Microbiol Resour Announc
James SA, Parker A, Purse C, Baker DJ, Funnell SGP, Carding SR.   +5 more
europepmc   +1 more source

Yellow fever and dengue fever viruses serosurvey in non-human primates of the Kedougou forest galleries in Southeastern Senegal

, 2014
Massamba Sylla, Dubot-Peres Audrey, Daouda Mbengue Sylla Elhadji, Molez Jean-Franois, Ndiaye Mady, Xavier Pourrut, Gonzalez Jean-Paul   +6 more
openalex   +2 more sources

PharmVar GeneFocus: NAT2—Genetic Variation and Updated Nomenclature

Clinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human N‐acetyltransferase 2 (NAT2) gene. NAT2 metabolizes several clinically used drugs including isoniazid, hydralazine, amifampridine, procainamide, and sulfonamides such as dapsone, and also some highly carcinogenic arylamines.
Georgia Papanikolaou, Estella S. Poloni, José A.G. Agúndez, Raquel L.F. Teixeira, Erin C. Boone, Adalberto Rezende Santos, Michelle Whirl‐Carrillo, Katrin Sangkuhl, Teri E. Klein, Mariam R. Habil, Giannoulis Fakis, Rodney F. Minchin, David W. Hein, Sotiria Boukouvala, Andrea Gaedigk   +14 more
wiley   +1 more source

Cholesterol metabolism and neuroinflammatory changes in a non-human primate spinal nerve ligation model. [PDF]

Sci Rep
Yamane H, Koyama S, Komatsu T, Tanaka T, Koguchi R, Watanabe H, Nishiura M, Yoshikawa S, Iimura T.   +8 more
europepmc   +1 more source