Results 21 to 30 of about 120,353 (299)

Beyond MRI: on the scientific value of combining non-human primate neuroimaging with metadata

open access: yesNeuroImage, 2021
Sharing and pooling large amounts of non-human primate neuroimaging data offer new exciting opportunities to understand the primate brain. The potential of big data in non-human primate neuroimaging could however be tremendously enhanced by combining ...
Colline Poirier   +8 more
doaj   +1 more source

Bioactive Peptides and Proteins from Wasp Venoms

open access: yesBiomolecules, 2022
Wasps, members of the order Hymenoptera, use their venom for predation and defense. Accordingly, their venoms contain various constituents acting on the circulatory, immune and nervous systems.
Lei Luo, Peter Muiruri Kamau, Ren Lai
doaj   +1 more source

Anticarin β Inhibits Human Glioma Progression by Suppressing Cancer Stemness via STAT3

open access: yesFrontiers in Oncology, 2021
Glioma is the most common form of malignant brain cancer. It is very difficult to cure malignant glioma because of the presence of glioma stem cells, which are a barrier to cure, have high tumorigenesis, associated with drug resistance, and responsible ...
Min Zhang   +5 more
doaj   +1 more source

GAS-STING: a classical DNA recognition pathways to tumor therapy

open access: yesFrontiers in Immunology, 2023
Cyclic GMP-AMP synthetase (cGAS), recognized as the primary DNA sensor within cells, possesses the capability to identify foreign DNA molecules along with free DNA fragments.
Xinrui Wang   +10 more
doaj   +1 more source

Anticarin-β shows a promising anti-osteosarcoma effect by specifically inhibiting CCT4 to impair proteostasis

open access: yesActa Pharmaceutica Sinica B, 2022
Unlike healthy, non-transformed cells, the proteostasis network of cancer cells is taxed to produce proteins involved in tumor development. Cancer cells have a higher dependency on molecular chaperones to maintain proteostasis.
Gan Wang   +21 more
doaj   +1 more source

An effort to use human-based exome capture methods to analyze chimpanzee and macaque exomes. [PDF]

open access: yesPLoS ONE, 2012
Non-human primates have emerged as an important resource for the study of human disease and evolution. The characterization of genomic variation between and within non-human primate species could advance the development of genetically defined non-human ...
Xin Jin   +34 more
doaj   +1 more source

Non-Human Primate Models of Tuberculosis

open access: yesMicrobiology Spectrum, 2016
ABSTRACT Among the animal models of tuberculosis (TB), the non-human primates, particularly rhesus macaques ( Macaca fascicularis ) and cynomolgus macaques ( Macaca mulatta ), share the greatest anatomical and physiological similarities with humans.
Juliet C, Peña, Wen-Zhe, Ho
openaire   +2 more sources

Strengths and challenges of longitudinal non-human primate neuroimaging

open access: yesNeuroImage, 2021
Longitudinal non-human primate neuroimaging has the potential to greatly enhance our understanding of primate brain structure and function. Here we describe its specific strengths, compared to both cross-sectional non-human primate neuroimaging and ...
Xiaowei Song   +11 more
doaj   +1 more source

Aging in Non-Human Primate Society: What Relevance for Social Gerontology?

open access: yesAnthropology & Aging, 2023
Wild animals were once thought not to age, as their deaths were viewed as the consequences of constant exposure to the perennial risks of nature. Studies of non-human aging were largely confined to biological investigations, focusing upon short-lived ...
Chris Gilleard
doaj   +1 more source

Genetic Diagnostic Yield and Novel Causal Genes of Congenital Heart Disease

open access: yesFrontiers in Genetics, 2022
Congenital heart disease (CHD) is the most common congenital malformation in fetuses and neonates, which also represents a leading cause of mortality.
Meihua Tan   +13 more
doaj   +1 more source

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