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Theories about evolutionary origins of human hepatitis B virus in primates and humans
Introduction: The human hepatitis B virus causes acute and chronic hepatitis and is considered one of the most serious human health issues by the World Health Organization, causing thousands of deaths per year.
Breno Frederico de Carvalho Dominguez Souza +4 more
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The Chinese tree shrew (Tupaia belangeri chinensis) has the potential to replace the use of non-human primates in biomedical research. To increase the availability of this species, we have undertaken the ambitious task of establishing inbred lines of the
Jia-Qi Chen +7 more
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Microbiome Studies in Non-human Primates [PDF]
Observations of differing bacterial, intestinal microbiomes in people living with HIV have propelled interest in contributions of the microbiome to HIV disease. Non-human primate (NHP) models of HIV infection provide a controlled setting for assessing contributions of the microbiome by standardizing environmental confounders.
Brenchley, Jason M., Ortiz, Alexandra M.
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As an antioxidant, procyanidin B1(PB1) can improve the development of somatic cell nuclear transfer (SCNT) embryos; PB1 reduces the level of oxidative stress (OS) during the in vitro development of SCNT embryos by decreasing the level of reactive oxygen ...
Wei Gao +6 more
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Summary: Background: The Coronavirus Disease 2019 (COVID-19) pandemic has been a great threat to global public health since 2020. Although the advance on vaccine development has been largely achieved, a strategy to alleviate immune overactivation in ...
Jianxiong Zeng +11 more
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Bioactive Peptides and Proteins from Centipede Venoms
Venoms are a complex cocktail of biologically active molecules, including peptides, proteins, polyamide, and enzymes widely produced by venomous organisms.
Yalan Han +3 more
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The non‐human primate model of tuberculosis [PDF]
AbstractNon‐human primates (NHPs) are used to model human disease owing to their remarkably similar genomes, physiology, and immune systems. Recently, there has been an increased interest in modeling tuberculosis (TB) in NHPs. Macaques are susceptible to infection with different strains of Mycobacterium tuberculosis (Mtb), producing the full spectrum ...
D, Kaushal +3 more
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Bioactive Peptides and Proteins from Wasp Venoms
Wasps, members of the order Hymenoptera, use their venom for predation and defense. Accordingly, their venoms contain various constituents acting on the circulatory, immune and nervous systems.
Lei Luo, Peter Muiruri Kamau, Ren Lai
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Anticarin β Inhibits Human Glioma Progression by Suppressing Cancer Stemness via STAT3
Glioma is the most common form of malignant brain cancer. It is very difficult to cure malignant glioma because of the presence of glioma stem cells, which are a barrier to cure, have high tumorigenesis, associated with drug resistance, and responsible ...
Min Zhang +5 more
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Neuroimaging of Non-Human Primates [PDF]
Welcome to this special issue of the Open Neuroimaging Journal which focuses on neuroimaging studies of non-human primates (NHPs) as presented by leaders in the field. NHPs are important animal models because of their genetic, ontogenic, and physiological similarities to humans.
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