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Challenges of modeling pristane‐induced lupus in non‐human primates [PDF]
Animal Models and Experimental MedicineA lupus‐like condition induced by intraperitoneal administration of pristane (2,6,10,14‐tetramethylpentadecane) in mice is widely used as a model of systemic lupus erythematosus (SLE). Due to their phylogenetic distance from humans, murine models are not
Elena Vladimirovna Vinogradova +5 more
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Animals, 2022 The Chinese tree shrew (Tupaia belangeri chinensis) has the potential to replace the use of non-human primates in biomedical research. To increase the availability of this species, we have undertaken the ambitious task of establishing inbred lines of the
Jia-Qi Chen +7 more
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Molecules, 2021 As an antioxidant, procyanidin B1(PB1) can improve the development of somatic cell nuclear transfer (SCNT) embryos; PB1 reduces the level of oxidative stress (OS) during the in vitro development of SCNT embryos by decreasing the level of reactive oxygen ...
Wei Gao +6 more
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EBioMedicine, 2022 Summary: Background: The Coronavirus Disease 2019 (COVID-19) pandemic has been a great threat to global public health since 2020. Although the advance on vaccine development has been largely achieved, a strategy to alleviate immune overactivation in ...
Jianxiong Zeng +11 more
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Bioactive Peptides and Proteins from Centipede Venoms
Molecules, 2022 Venoms are a complex cocktail of biologically active molecules, including peptides, proteins, polyamide, and enzymes widely produced by venomous organisms.
Yalan Han +3 more
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Extrapolating from Laboratory Behavioral Research on Nonhuman Primates Is Unjustified [PDF]
, 2020 Conducting research on animals is supposed to be valuable because it provides information on how human mechanisms work. But for the use of animal models to be ethically justified, it must be epistemically justified.
Crutchfield, Parker
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Memory B cells and CD8⁺ lymphocytes do not control seasonal influenza A virus replication after homologous re-challenge of rhesus macaques. [PDF]
, 2011 This study sought to define the role of memory lymphocytes in the protection from homologous influenza A virus re-challenge in rhesus macaques. Depleting monoclonal antibodies (mAb) were administered to the animals prior to their second experimental ...
Carroll, Timothy D +4 more
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Of apples and oranges? The evolution of “monogamy” in non-human primates [PDF]
, 2020 Behavioral ecologists, evolutionary biologists, and anthropologists have been long fascinated by the existence of “monogamy” in the animal kingdom.
Di Fore, Anthony +2 more
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Bioactive Peptides and Proteins from Wasp Venoms
Biomolecules, 2022 Wasps, members of the order Hymenoptera, use their venom for predation and defense. Accordingly, their venoms contain various constituents acting on the circulatory, immune and nervous systems.
Lei Luo, Peter Muiruri Kamau, Ren Lai
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Anticarin β Inhibits Human Glioma Progression by Suppressing Cancer Stemness via STAT3
Frontiers in Oncology, 2021 Glioma is the most common form of malignant brain cancer. It is very difficult to cure malignant glioma because of the presence of glioma stem cells, which are a barrier to cure, have high tumorigenesis, associated with drug resistance, and responsible ...
Min Zhang +5 more
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