Results 81 to 90 of about 317,227 (291)

Application of biochemical and polymerase chain reaction assays for identification of Campylobacter isolates from non-human primates

Memorias do Instituto Oswaldo Cruz, 2006
A multiplex polymerase chain reaction (PCR) assay was performed on 167 thermophilic campylobacters isolated from non-human primates. Samples were first identified by phenotypic methods resulting in 64 Campylobacter jejuni and 103 C. coli strains.
Mônica de Castro Britto Vilardo, Jacqueline Darc da Silva Thomé, Wagner Thadeu Cardoso Esteves, Ana Luzia Lauria Filgueiras, Selma Soares de Oliveira   +4 more
doaj   +1 more source

Forelimb movements evoked by optogenetic stimulation of the macaque motor cortex

Nature Communications, 2020
Non-human primates are useful models for understanding the human brain but application of optogenetics to non-human primates is challenging. The authors used optogenetic intracortical microstimulation in the primary motor cortex of macaques to elicit ...
Hidenori Watanabe, Hiromi Sano, Satomi Chiken, Kenta Kobayashi, Yuko Fukata, Masaki Fukata, Hajime Mushiake, Atsushi Nambu   +7 more
doaj   +1 more source

Use of adeno-associated virus-mediated delivery of mutant huntingtin to study the spreading capacity of the protein in mice and non-human primates

Neurobiology of Disease, 2020
In order to model various aspects of Huntington's disease (HD) pathology, in particular protein spread, we administered adeno-associated virus (AAV) expressing green fluorescent protein (GFP) or GFP coupled to HTT-Exon1 (19Q or 103Q) to the central ...
Alexander Maxan, Giacomo Sciacca, Melanie Alpaugh, Zhu Tao, Ludivine Breger, Benjamin Dehay, Zhang Ling, Qin Chuan, Giulia Cisbani, Maria Masnata, Shireen Salem, Steve Lacroix, Abid Oueslati, Erwan Bezard, Francesca Cicchetti   +14 more
doaj   +1 more source

Evolution as Connecting First-Person and Third-Person Perspectives of Consciousness [PDF]

, 2008
First-person and third-person perspectives are different items of human consciousness.\ud Feeling the taste of a fruit or being consciously part of a group eating fruits call for different perspectives of\ud consciousness.
Menant, Christophe
core  

Potential benefits and risks of clinical xenotransplantation [PDF]

, 2012
The transplantation of organs and cells from pigs into humans could overcome the critical and continuing problem of the lack of availability of deceased human organs and cells for clinical transplantation.
Ayares, D, Cooper, DKC
core   +2 more sources

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Transferrin Disassociates TCR from CD3 Signaling Apparatus to Promote Metastasis

Research
Immune recognition and activation by the peptide-laden major histocompatibility complex–T cell receptor (TCR)–CD3 complex is essential for anti-tumor immunity. Tumors may escape immune surveillance by dissembling the complex.
Ruomei Cheng, Xiaopeng Tang, Qiyu Zhao, Yuming Wang, Wenlin Chen, Gan Wang, Chenxi Wang, James Mwangi, Qiumin Lu, Dawit Adisu Tadese, Xudong Zhao, Caiwen Ou, Ren Lai   +12 more
doaj   +1 more source

Animal models of the non-motor features of Parkinson's disease

Neurobiology of Disease, 2012
The non-motor symptoms (NMS) of Parkinson's disease (PD) occur in roughly 90% of patients, have a profound negative impact on their quality of life, and often go undiagnosed.
Kimberly McDowell, Marie-Françoise Chesselet   +1 more
doaj   +1 more source

Using natural ecology to predict higher cognition in human and non-human primates [PDF]

Animal Behavior and Cognition, 2019
Many critical aspects of contemporary human cognitive functionality (e.g., reading, fixing a car) evolved historically in a time frame that biological natural selection cannot account for.
Bennett L. Schwartz
doaj   +1 more source

Convergent evolution of pregnancy-specific glycoproteins in human and horse [PDF]

, 2016
Pregnancy-specific glycoproteins (PSGs) are members of the carcinoembryonic antigen cell adhesion molecule (CEACAM) family that are secreted by trophoblast cells. PSGs may modulate immune, angiogenic and platelet responses during pregnancy.
Amanda M de Mestre, Baker, Denis Aleksic, Donaldson, Fialova, Jana Hänske, Johannes Handler, Jordan E Read, Lisa Blaschke, Robert Kammerer, Ronan O’Riordan, Schumacher, Sophie Mißbach, Tom Moore, Victoria Cabrera-Sharp, Wiebke Weiß, Wolfgang Zimmermann   +16 more
core   +2 more sources