Results 51 to 60 of about 24,187 (251)

Adalimumab in the treatment of non-infectious uveitis

Advances in Clinical and Experimental Medicine, 2020
Non-infectious uveitis (NIU) is a serious sight-threatening condition whose pathogenesis is often autoimmune in nature. It may manifest in any age group, though adults aged 20-50 are the group most often affected. It causes 5-10% of visual impairment worldwide.
Alicja Burek-Michalska, Anna Turno-Kręcicka   +1 more
openaire   +3 more sources

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Intraocular Implants for the Treatment of Autoimmune Uveitis

Journal of Functional Biomaterials, 2015
Uveitis is the third leading cause of blindness in developed countries. Currently, the most widely used treatment of non-infectious uveitis is corticosteroids.
Darren J. Lee
doaj   +1 more source

Clinical Variations of Uveitis in Immuno-Inflammatory Diseases. Review of the Literature. Part 2

Oftalʹmologiâ, 2023
In the previous part of the review clinical and diagnostic aspects of some non-infectious uveitis in patients with immunoinflammatory diseases were discussed.
G. A. Davydova, T. A. Lisitsyna, L. A. Kovaleva, E. S. Sorozhkina, A. A. Zaitseva, A. A. Baisangurova   +5 more
doaj   +1 more source

Juvenile idiopathic arthritis-associated uveitis [PDF]

, 2016
Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease of childhood, with JIA-associated uveitis its most common extra-articular manifestation.
Clarke, Sarah, Ramanan, Athimalaipet, Sen, Ethan   +2 more
core   +3 more sources

Increased Anti‐Psoriatic Effect of Anti‐Inflammatory Dendrimers Using Fluid Catanionic Vesicle‐Based Topical Formulations

Advanced Healthcare Materials, EarlyView.
Next‐Generation Psoriasis Therapy – With advanced dendrimer‐based formulations, this study paves the way for highly effective, skin‐permeable treatments. Encapsulated in fluid catanionic vesicles, IMD‐006 and its analogues show promising anti‐psoriatic effects offering a targeted, non‐invasive approach to managing chronic skin inflammation.
Ranime Jebbawi, Abdelouahd Oukhrib, Emily Clement, Hélène Labie, Stéphanie Cassel, Séverine Fruchon, Anne‐Marie Caminade, Michel Simon, Rémy Poupot, Cédric‐Olivier Turrin, Muriel Blanzat   +10 more
wiley   +1 more source

Demography in Swiss paediatric uveitis: a retrospective cohort study

Journal of Ophthalmic Inflammation and Infection
Introduction Paediatric uveitis is a rare disease. It can affect any segment and have various etiologies, including infectious, autoimmune, and masquerade diseases.
Jeanne Martine Gunzinger, Alice Kitay, Fabio Meier, Christian Böni, Seraina Palmer Sarott, Brigitte Simonsz-Tóth, Christina Gerth-Kahlert   +6 more
doaj   +1 more source

Low-volume multiplex solid-phase PCR without DNA extraction for etiological diagnosis of infectious uveitis

Indian Journal of Ophthalmology
Purpose: To evaluate the usefulness of a low-volume multiplex direct polymerase chain reaction (PCR) in identifying pathogens in intraocular fluid in infectious uveitis. Design: Prospective interventional non-comparative study.
Eduardo Ferracioli-Oda, Tatiana Tanaka, Michele Soares Gomes Gouvea, João Renato Rebello Pinho, Verônica Coelho, Paulo José Martins Bispo, Carlos Eduardo Hirata, Joyce Hisae Yamamoto   +7 more
doaj   +1 more source

mTOR-inhibiting pharmacotherapy for the treatment of non-infectious uveitis: a systematic review protocol

Systematic Reviews, 2018
Background Non-infectious uveitis represents a sub-type of intraocular inflammation often associated with disorders of immune dysregulation. If untreated, the intraocular inflammation may progress to severe visual impairment and blindness.
Joshua Blair, Robert Barry, Philip I. Murray, David J. Moore, Alastair K. Denniston   +4 more
doaj   +1 more source

Non-Infectious Uveitis in Childhood – Preliminary Results

Bulgarian Review of Ophthalmology, 2022
The purpose of the present study was to extend our knowledge of the occurrence, characteristics, severity and prognosis of uveitis in children with juvenile idiopathic arthritis (JIA). A total of 31 children with autoimmune diseases (usually associated with noninfectious uveitis) or isolated noninfectious uveitis were studied. The most of the cases are
Markova, M.; Medical University – Sofia, Stefanov, S.; SHATCD “Prof. Iv. Mitev” – Sofia, Telcharova, A.; SHATCD “Prof. Iv. Mitev” – Sofia, Oskar, A.; Medical University – Sofia   +3 more
openaire   +2 more sources