Results 41 to 50 of about 35,823 (237)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Efficient and Parallel Implementation of Isogeny-based Deterministic Group Actions
Transactions on Cryptographic Hardware and Embedded SystemsRecent work by Houben (Asiacrypt’25) introduced a new formulation for class group actions on supersingular elliptic curves oriented by an imaginary quadratic order for an arbitrarily large discriminant.
Weize Wang +3 more
doaj +1 more source
COGITA network has constructed a glossary of diagnostic reasoning terms
European Journal of General Practice, 2017 The role of gut feelings in diagnostic reasoning is recognized by most GPs throughout Europe, and probably throughout the world. Studies on this topic have emerged from different countries but there is the risk that authors will use different terms for ...
Marie Barais +5 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Organizing Relational Complexity—Design of Interactive Complex Systems
Multimodal Technologies and InteractionWith the advent of AI- and robot-systems, the current Human–Computer Interaction (HCI) paradigm, which treats interaction as a transactional exchange, is increasingly insufficient for complex socio-technical systems.
Linus de Petris, Siamak Khatibi
doaj +1 more source
Description of Organizational Learning Network and Identification of Factors Influencing Its Formation Using Network Analysis Method (Case Study: Khorasan Regional Electric Company [PDF]
مدیریت راهبردی دانش سازمانیPurpose: In modern organizations, where survival and growth depend heavily on agility and the ability to respond to rapid changes in the external environment, facilitating an efficient learning process and integrating it into the daily operations of ...
Zahra Ghaffarian Sokhanvar +2 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
A comparative study of the impact of entrepreneurship and innovation in developing and developed economic systems. [PDF]
رویکردهای نوین در مدیریت و بازاریابیThe aim of this research is to identify the factors affecting the energy market ecosystem (Case Study of the Iranian Electricity Market). The research method is applicable-exploratory in terms of its purpose, and qualitative in terms of its ...
Pouria Mahmoudi +2 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
مجله آب و خاک, 2016 Introduction: Phosphorus (P) is considered to be one of the most essential macro elements required for growth and development of plants, but, due to low solubility and fixation in soils, only a small fraction of phosphorus in soil (1 ppm or 0.1%) is ...
S. Nikmehr, A. Akhgar
doaj +1 more source