Results 61 to 70 of about 108,821 (296)

FAST: A Novel, Executive Function-Based Approach to Cognitive Enhancement

Frontiers in Human Neuroscience, 2019
The present study introduces a novel cognitive intervention aimed at improving fluid intelligence (Gf), based on a framework we refer to as FAST: Flexible, Adaptive, Synergistic Training.
Jessamy Norton-Ford Almquist, Santosh Mathan, Anna-Katharine Brem, Anna-Katharine Brem, Franziska Plessow, James McKanna, Emiliano Santarnecchi, Alvaro Pascual-Leone, Roi Cohen Kadosh, Misha Pavel, Nick Yeung   +10 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Efficacy of transcranial magnetic stimulation treatment in reducing neuropsychiatric symptomatology after traumatic brain injury

Frontiers in Neurology
BackgroundNeuropsychiatric disorders are highly disabling in traumatic brain injury (TBI) patients, and psychopharmacological treatments often fail to adequately mitigate their detrimental effects.
Gianna Carla Riccitelli, Gianna Carla Riccitelli, Riccardo Borgonovo, Mariasole Villa, Emanuele Pravatà, Emanuele Pravatà, Alain Kaelin-Lang, Alain Kaelin-Lang, Alain Kaelin-Lang   +8 more
doaj   +1 more source

Investigating the sex-dependent effects of prefrontal cortex stimulation on response execution and inhibition

Biology of Sex Differences, 2021
Highlights 1. In a fully counterbalanced (for sex and all experimental conditions), sham-controlled cross-over study, we examined the effects of tDCS over the left DLPFC in the context of Stop-Signal task. 2.
Daniel J. Fehring, Ranshikha Samandra, Zakia Z. Haque, Shapour Jaberzadeh, Marcello Rosa, Farshad A. Mansouri   +5 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Combining transcranial electrical stimulation with training in older adults: Effects on dual-task ability

Neurotherapeutics
Background: Enhancing dual-task (DT) performance in older adults through cognitive improvement may help prevent neurodegenerative decline. Objective: This study aimed to investigate the efficacy of combining repeated transcranial electrical stimulation ...
Yong Jiang, Azadeh Lesani, Xue Guo, Isabella Wistuba, Raquel Guiomar, Denis Glage, Perianen Ramasawmy, Andrea Antal   +7 more
doaj   +1 more source

Large-scale analysis of interindividual variability in theta-burst stimulation data: Results from the ‘Big TMS Data Collaboration’

Brain Stimulation, 2020
Background: Many studies have attempted to identify the sources of interindividual variability in response to theta-burst stimulation (TBS). However, these studies have been limited by small sample sizes, leading to conflicting results.
Daniel T. Corp, Hannah G.K. Bereznicki, Gillian M. Clark, George J. Youssef, Peter J. Fried, Ali Jannati, Charlotte B. Davies, Joyce Gomes-Osman, Julie Stamm, Sung Wook Chung, Steven J. Bowe, Nigel C. Rogasch, Paul B. Fitzgerald, Giacomo Koch, Vincenzo Di Lazzaro, Alvaro Pascual-Leone, Peter G. Enticott   +16 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A novel tDCS sham approach based on model-driven controlled shunting

Brain Stimulation, 2020
Background: Transcranial direct current stimulation (tDCS), a non-invasive brain stimulation technique able to transiently modulate brain activity, is surging as one of the most promising therapeutic solutions in many neurological and psychiatric ...
Francesco Neri, Lucia Mencarelli, Arianna Menardi, Fabio Giovannelli, Simone Rossi, Giulia Sprugnoli, Alessandro Rossi, Alvaro Pascual-Leone, Ricardo Salvador, Giulio Ruffini, Emiliano Santarnecchi   +10 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source