Results 21 to 30 of about 42,912 (201)

Non-invasive prenatal testing: ethical issues explored [PDF]

European Journal of Human Genetics, 2009
This paper explores the ethical implications of introducing non-invasive prenatal diagnostic tests (NIPD tests) in prenatal screening for foetal abnormalities. NIPD tests are easy and safe and can be performed early in pregnancy. Precisely because of these features, it is feared that informed consent may become more difficult, that both testing and ...
de Jong, Antina, Dondorp, Wybo J., de Die-Smulders, Christine E. M., Frints, Suzanne G. M., de Wert, Guido M. W. R.   +4 more
openaire   +2 more sources

Non invasive prenatal testing for single gene disorders:Exploring the ethics [PDF]

, 2012
Non-invasive prenatal testing for single gene disorders is now clearly on the horizon. This new technology offers obvious clinical benefits such as safe testing early in pregnancy.
A de Jong, A Hall, A Sommerville, A van den Heuvel, AJ Newson, AN Barrett, B Heyman, B Modell, BA Bernhardt, C Baillie, C Lewis, C Lewis, C Meaney, Celine Lewis, E Dormandy, E Garcia, F Mujezinovic, FL Raymond, FM Lun, FM Lun, H Skirton, HC Fan, J Garcia, J Hodgson, J Narveson, JC Sapp, KM Finning, KT Maliszewski, L Henneman, L Kooij, L Locock, LC Sayres, LS Chitty, Lyn S Chitty, M Berkenstadt, M Hill, M Hill, M Hill, M McAllister, M Nicol, M van den Berg, Melissa Hill, N Press, NB Tsui, O O’Neil, PA Benn, R Chadwick, R Favre, R Rapp, S Galbiati, S Sherwin, SA Metcalfe, SE Kelly, SE Kelly, T Beauchamp, T Lau, TM Marteau, V Bot-Robin, V Seavilleklein, V Tsianakas, V Tsianakas, Y Lo, YM Lo, YM Lo, Z Deans, Zuzana Deans   +65 more
core   +2 more sources

Non-Invasive Prenatal Testing (NIPT): Reliability, Challenges, and Future Directions

Diagnostics, 2023
Non-invasive prenatal testing was first discovered in 1988; it was primarily thought to be able to detect common aneuploidies, such as Patau syndrome (T13), Edward Syndrome (T18), and Down syndrome (T21).
Siva Shantini Jayashankar, Muhammad Luqman Nasaruddin, Muhammad Faiz Hassan, Rima Anggrena Dasrilsyah, Mohamad Nasir Shafiee, Noor Akmal Shareela Ismail, Ekram Alias   +6 more
doaj   +1 more source

Routinization of prenatal screening with the non-invasive prenatal test: pregnant women’s perspectives [PDF]

European Journal of Human Genetics, 2021
AbstractDue to the favorable test characteristics of the non-invasive prenatal test (NIPT) in the screening of fetal aneuploidy, there has been a strong and growing demand for implementation. In the Netherlands, NIPT is offered within a governmentally supported screening program as a first-tier screening test for all pregnant women (TRIDENT-2 study ...
Karuna R. M. van der Meij, Annabel Njio, Linda Martin, Janneke T. Gitsels-van der Wal, Mireille N. Bekker, Elsbeth H. van Vliet-Lachotzki, A. Jeanine E. M. van der Ven, Adriana Kater-Kuipers, Danielle R. M. Timmermans, Erik A. Sistermans, Robert-Jan H. Galjaard, Lidewij Henneman   +11 more
openaire   +4 more sources

Non-invasive prenatal diagnosis (NIPD) for single gene disorders: cost analysis of NIPD and invasive testing pathways [PDF]

, 2016
OBJECTIVE: Evaluate the costs of offering non-invasive prenatal diagnosis (NIPD) for single gene disorders compared to traditional invasive testing to inform NIPD implementation into clinical practice.
Chitty, LS, Drury, S, Hill, M, Jenkins, L, Mason, S, Morris, S, Verhoef, TI   +6 more
core   +1 more source

Controversies in implementing non‐invasive prenatal testing in a public antenatal care program

Acta Obstetricia et Gynecologica Scandinavica, 2022
Women's autonomy and an inclusive society for all individuals are highly valued in Norway. The Norwegian Biotechnology Act changed in 2020 allowing first‐trimester screening and cell‐free DNA for common trisomies to all pregnant women.
Kjell Åsmund Blix Salvesen, Ragnhild Glad, Vasilis Sitras   +2 more
doaj   +1 more source

Preferences for Prenatal Tests for Cystic Fibrosis: A Discrete Choice Experiment to Compare the Views of Adult Patients, Carriers of Cystic Fibrosis and Health Professionals [PDF]

, 2014
As new technologies enable the development of non-invasive prenatal diagnosis (NIPD) for cystic fibrosis (CF), research examining stakeholder views is essential for the preparation of implementation strategies.
Chitty, L, Hill, M, Morris, S, Nash, E, Suri, R   +4 more
core   +1 more source

Innovative method for reducing uninformative calls in non-invasive prenatal testing [PDF]

, 2018
Non-invasive prenatal testing or NIPT is currently among the top researched topic in obstetric care. While the performance of the current state-of-the-art NIPT solutions achieve high sensitivity and specificity, they still struggle with a considerable ...
Budis, Jaroslav, Duris, Frantisek, Gazdarica, Juraj, Gazdaricova, Iveta, Harsanyova, Maria, Kucharik, Marcel, Minarik, Gabriel, Nagy, Balint, Radvanszky, Jan, Sekelska, Martina, Strieskova, Lucia, Szemes, Tomas, Szucs, Gabor, Turna, Jan   +13 more
core   +2 more sources

Challenges and clinical implications of discordant non-invasive prenatal testing results: insights from two case studies [PDF]

Folia Medica
Non-invasive prenatal testing (NIPT) has transformed prenatal screening, offering high sensitivity and specificity in the detection of common fetal aneuploidies.
Slavyana Galeva, Boris Stoilov, Ekaterina Uchikova   +2 more
doaj   +3 more sources

Genetic Counseling and Management: The First Study to Report NIPT Findings in a Romanian Population

Medicina, 2022
Background and Objectives: Non-invasive prenatal testing (NIPT) has been confirmed as the most accurate screening test for trisomies 21, 18, 13, sex chromosomes aneuploidies and several microdeletions. This study aimed to assess the accuracy of cell free
Cristina Gug, Ioana Mozos, Adrian Ratiu, Anca Tudor, Eusebiu Vlad Gorduza, Lavinia Caba, Miruna Gug, Catalina Cojocariu, Cristian Furau, Gheorghe Furau, Monica Adriana Vaida, Dorina Stoicanescu   +11 more
doaj   +1 more source