Results 31 to 40 of about 262,123 (293)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Removal of non-metallic inclusion by ceramic filter.

open access: yesTransactions of the Iron and Steel Institute of Japan, 1987
YAMADA, Keizo   +4 more
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Overview of application of automated SEM/EDS measurements for inclusion characterization in steelmaking

open access: yesMetalMat
The scanning electron microscope equipped with an energy dispersive spectroscopy (SEM/EDS) is considered as a state‐of‐the‐art characterization tool to determine the morphological features and the chemical composition of non‐metallic inclusions in steel.
Shashank Ramesh Babu   +1 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Non-metallic inclusions and plasticity of steels

open access: yes, 2020
The problems of the influence of non-metallic inclusions in the technological plasticity and mechanical properties of steels are discussed. The results of the study of deformation and destruction of non-metallic inclusions in steel treatment pressure in various conditions were listed.
Gubenko, S., Mamuzić, Ilija
openaire   +3 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Study on Control Technology of Non-metallic Inclusions in 25MnBM Steel for Track Plate

open access: yesTeshugang, 2020
The 25MnBM track plate steel is produced by 50 ton EAF short process. The control technology of TiN inclusions and the effect of RE on non-metallic inclusions in 25MnBM of steel are studied.
卢乃双, 梁娜, 黄涛
doaj  

Methods for reducing nonmetallic inclusions in coatings applied by laser surfacing

open access: yesRUDN Journal of Engineering Research, 2023
The results of experimental studies based on the analysis of deposited coatings and processing methods aimed at reducing the number of non-metallic inclusions in the process of laser powder cladding are presented.
Alexey V. Zavitkov   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

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