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Non-motor symptoms: Identification and management
Parkinsonism & Related Disorders, 2007Non-motor symptoms are an important part of Parkinson's disease (PD) symptoms complex. They cause a significant burden on the quality of life of patients and their carers and remain a major cause of hospitalisation. Treatment of non-motor symptoms can be challenging as these symptoms are often unresponsive to conventional dopaminergic therapy. However,
Muzerengi, Sharon +2 more
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Non-motor symptoms in Parkinson's disease
Parkinsonism & Related Disorders, 2016With the growing awareness of the presence of non-motor symptoms in Parkinson's disease (PD) has come the realization that these non-motor features play a tremendously important, and sometimes dominant, role in the management and even the diagnosis of the disorder.
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Non‐motor symptoms in Parkinson’s disease
European Journal of Neurology, 2008Although still considered a paradigmatic movement disorder, Parkinson’s disease (PD) is associated with a broad spectrum of non‐motor symptoms. These include disorders of mood and affect with apathy, anhedonia and depression, cognitive dysfunction and hallucinosis, as well as complex behavioural disorders.
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Overlooked non-motor symptoms in myasthenia gravis
Journal of Neurology, Neurosurgery & Psychiatry, 2012Patients with myasthenia gravis (MG) may have various non-motor symptoms in addition to fatigability and weakness of skeletal muscles. Thymomas contain abundant immature thymocytes and developing CD4 and CD8 T cells. Thymomas are found in 15-25% of patients with MG and are associated with severe symptoms. We suggest that non-motor symptoms are based on
Shigeaki, Suzuki +2 more
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[Non-motor symptoms of Parkinson's disease].
Nederlands tijdschrift voor geneeskunde, 2012Parkinson's disease has traditionally been viewed as a disease with only motor features. Nowadays, a wide variety of non-motor symptoms and signs are also recognised as being characteristic of the disease. Non-motor symptoms, most importantly autonomic dysfunction, neuropsychiatric symptoms and sleep problems, are prevalent in virtually all Parkinson's
Weerkamp, N.J., Nijhof, A., Tissingh, G.
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Recognizing non-motor Parkinson's symptoms
Practice Nursing, 2008The Parkinson's Disease Society is offering short education sessions to general practices to increase the understanding of issues faced by patients. Brian Senior explains
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Comprehensive Non-motor Symptoms Assessments
2014There are two instruments available for assessing a wide variety of non-motor symptoms (NMS) that may be present in Parkinson’s disease (PD). One is completed by the patient, and the other by the clinician. Once identified, some NMS may be assessed in more detail with specific scales, such as those described in Chapter 6.
Pablo Martinez-Martin +3 more
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Non-Motor Symptoms in Parkinson's Disease
2023Parkinson's disease (PD) is a multisystem disorder considered the second most common neurodegenerative disease worldwide of which neuroprotective therapies are not yet available. PD is known mainly by its cardinal motor symptoms which are believed to be associated with dopamine deficiency in the nigrostriatal pathway as a result of DAergic neurons ...
Bilal El-Mansoury +14 more
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[Non-motor symptoms in Parkinson's disease].
Ugeskrift for laeger, 2021Parkinson's disease is a neurodegenerative movement disorder with a broad spectrum of both motor- and non-motor symptoms. A new top-down model for pathogenesis has recently been suggested, supporting the hypothesis on onset of prodromal non-motor features several years before motor symptoms.
Nick Schou, Nielsen +1 more
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The Burden of Non-Motor Symptoms
2011Although most of the symptoms of Parkinson’s disease (PD) seem to be motor-based, the non-motor symptoms (NMSs) of PD, often overshadowed, also constitute a major clinical challenge. The NMSs of PD, including neuropsychiatric, cognitive, gastrointestinal and sensory, not only are observed in later stages but also predominate in the early stages of PD ...
Maria Joao Forjaz +2 more
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