Results 81 to 90 of about 135,346 (336)

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

Robust Semi-Supervised Non-Negative Matrix Factorization With Structured Normalization

open access: yesIEEE Access, 2019
Non-negative matrix factorization (NMF) approximates a non-negative data matrix with the product of two low-rank non-negative matrices by minimizing the cost of such approximation.
Liujing Wang   +4 more
doaj   +1 more source

New SVD based initialization strategy for Non-negative Matrix Factorization

open access: yes, 2014
There are two problems need to be dealt with for Non-negative Matrix Factorization (NMF): choose a suitable rank of the factorization and provide a good initialization method for NMF algorithms.
Qiao, Hanli
core   +1 more source

Infinite Non-Negative Matrix Factorization

open access: yes, 2010
Publication in the conference proceedings of EUSIPCO, Aalborg, Denmark ...
Mørup, Morten, Schmidt, Mikkel
openaire   +2 more sources

Non-negative Matrix Factorization for Binary Data

open access: yesProceedings of the 7th International Joint Conference on Knowledge Discovery, Knowledge Engineering and Knowledge Management, 2015
We propose the Logistic Non-negative Matrix Factorization for decomposition of binary data. Binary data are frequently generated in e.g. text analysis, sensory data, market basket data etc. A common method for analysing non-negative data is the Non-negative Matrix Factorization, though this is in theory not appropriate for binary data, and thus we ...
Larsen, Jacob Søgaard   +1 more
openaire   +3 more sources

Non-Negative Matrix Factorizations for Multiplex Network Analysis [PDF]

open access: yesIEEE Transactions on Pattern Analysis and Machine Intelligence, 2019
Networks have been a general tool for representing, analyzing, and modeling relational data arising in several domains. One of the most important aspect of network analysis is community detection or network clustering. Until recently, the major focus have been on discovering community structure in single (i.e., monoplex) networks.
Vladimir Gligorijevic   +2 more
openaire   +5 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

A New Feature Extraction and Recognition Method for Microexpression Based on Local Non-negative Matrix Factorization

open access: yesFrontiers in Neurorobotics, 2020
Microexpression is usually characterized by short duration and small action range, and the existing general expression recognition algorithms do not work well for microexpression.
Junli Gao   +4 more
doaj   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Multifrontal Non-negative Matrix Factorization

open access: yes, 2020
Non-negative matrix factorization (Nmf) is an important tool in high-performance large scale data analytics with applications ranging from community detection, recommender system, feature detection and linear and non-linear unmixing. While traditional Nmf works well when the data set is relatively dense, however, it may not extract sufficient structure
Ramakrishnan Kannan, Piyush Sao
openaire   +3 more sources

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