Results 71 to 80 of about 7,757,311 (314)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Non-parametric 3D Shape Warping [PDF]

open access: yes2010 20th International Conference on Pattern Recognition, 2010
A method is presented for non-rigid alignment of a source shape to a target shape through estimating and interpolating point-wise correspondences between their surfaces given as point clouds. The resulting mapping can be non-smooth and non-isometric, relate shapes across large variations, and find partial matches. It does not require a parametric model
openaire   +2 more sources

Parametric and non-parametric species delimitation methods result in the recognition of two new Neotropical woody bamboo species [PDF]

open access: yes, 2015
The Neotropical woody bamboo genus Otatea is one of five genera in the subtribe Guaduinae. Of the eight described Otatea species, seven are endemic to Mexico and one is also distributed in Central and South America.
Eduardo Ruiz-Sánchez
core  

Hypothesis testing for two population means: parametric or non-parametric test? [PDF]

open access: yes, 2019
The parametric Welch t-test and the non-parametric Wilcoxon–Mann–Whitney, empirical and exponential empirical likelihood tests are commonly used for hypothesis testing of two population means.
Alenazi, Abdulaziz   +3 more
core   +1 more source

Genomic Selection for Drought Tolerance Using Genome-Wide SNPs in Maize

open access: yesFrontiers in Plant Science, 2017
Traditional breeding strategies for selecting superior genotypes depending on phenotypic traits have proven to be of limited success, as this direct selection is hindered by low heritability, genetic interactions such as epistasis, environmental-genotype
Thirunavukkarasu Nepolean   +6 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Bayesian non parametric modelling of Higgs pair production

open access: yesEPJ Web of Conferences, 2017
Statistical classification models are commonly used to separate a signal from a background. In this talk we face the problem of isolating the signal of Higgs pair production using the decay channel in which each boson decays into a pair of b-quarks ...
Scarpa Bruno, Dorigo Tommaso
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Shape identification method for specified deformed mode of free-form shells

open access: yesNihon Kikai Gakkai ronbunshu, 2014
In this paper, we present a shape identification method of free-form shells for controlling the static deformation mode to the desired one. It is assumed that the shell is varied in the out-of-plane direction to the surface and the thickness is constant.
Yang LIU, Masatoshi SHIMODA
doaj   +1 more source

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