Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Bridging and Bonding: A Case for Prioritizing Social and Organizational Connectedness in Non-Profit Literacy Programming. [PDF]
Int J Community Wellbeing, 2023 Gosine K, Parker DC, Gallagher T.
europepmc +1 more source
Why without Pay? The Intrinsic Motivation between Investment and Consumption in Unpaid Labour Supply [PDF]
This paper provides a theoretical model and an empirical investigation on unpaid labour regularly supplied in non profit organisations. The contribution is threefold.
Bruna, Bruno, Damiano, Fiorillo
core
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Hands-On educational model in Nigeria increases interest in STEM careers
Annals of Global Health, 2016 T. Ajayi +8 more
doaj +1 more source
Do non-profits make a difference? Evaluating non-profit vis-Ã -vis for-profit organisations in social services [PDF]
This CPB Document provides a framework for the evaluation of non-profit organisations. This framework addresses the question under which conditions, and, if so, in what way non-profits should be stimulated. Essentially, in order to answer these questions,
Joëlle Noailly +2 more
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Collaboration among psychological researchers, the government, and non-profit organizations for "Konkatsu" (marriage hunting) in Japan. [PDF]
Front Psychol, 2022 Nishimura T +6 more
europepmc +1 more source
Determinants of net profit of public and private sector commercial banks in India(2015-2017)-A non parametric study [PDF]
, 2020 J. Jothikumar
openalex +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source